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Name of the generic: prasugrel PRA-soo-grel PRA-soo-grel“PRA-soo-grel”
Drug class: platelet aggregation inhibitors

Medical examination was conducted by Sanjai Sinha, MD. The last update was on June 26, 2023.

What is Effient?

Effient can prevent platelets that are present in blood from clumping together and forming blood clots. A blood clot that is not wanted can be a result of certain blood vessels or heart ailments.Efficient is utilized in patients who've had balloon angioplasty to clear blocked arterial arteries following a cardiac attack or severe chest pain.Efficacy can help reduce your chance of suffering a stroke or heart attack.

Side effects of Effient

Seek medical attention immediately. If you exhibit symptoms of an allergy reaction to the Effient, such as hives, dizziness or chest pain, difficulty breathing, swelling of your lips, face, and tongue,Prasugrel can increase your chance of bleeding, which could be life-threatening or even fatal.

Contact your View Drug doctor immediately. If you suffer from:

  • Feelings of faintness or dizziness, which make you think that you might collapse are a telltale sign that something serious is amiss in your body.
  • Any bleeding that doesn't stop;
  • Brown or pink urine
  • Indications of a severe blood-clotting issue such as dark skin tone, spots of purple on or under the skin, your mouth, fever, rapid heart rate, weakening stomach pain, difficulty breathing, or jaundice (yellowing of the eyes or skin);
  • Symptoms of stomach bleeding such as bloody or tarry stool, vomiting, vomit, or blood that appears like coffee grounds
  • Symptoms of a stroke: sudden weakness or numbness (especially on the opposite side) and sudden, intense headache or slurred speech issues with balance or vision.

The risk of bleeding is greater for those who are older.Common side effects of Effient include:

  • Nosebleeds
  • Bleeding or easy bruising.
    This list does not encompass all potential adverse reactions of treatment with this medicine. Other side effects could occur. Contact your doctor for advice regarding medical adverse effects. You can report any symptoms to the fda at 1-800-fda-1088.


Do not use Effient if you suffer from active bleeding, like a stomach ulcer or bleeding from the brain, if you have suffered a stroke (or "mini-stroke"), or if you're scheduled to undergo surgery, specifically coronary bypass.Effective measures can increase your chance of bleeding that could be fatal or life-threatening. Call your doctor or seek medical emergency assistance when you experience bleeding that won't stop, if you experience bloody or black stools, if you vomit out the blood, or if your vomit appears to be coffee ground.It is possible that you will need to stop taking the medicine for a brief period prior to any dental procedure or surgery. Don't take Effient off the market unless your physician tells you to.If you are taking Effient and other Effient medications, you should not use NSAIDs (non-steroidal anti-inflammatory medications) without consulting your physician. These comprise ibuprofen (Motrin, Advil) and naproxen (Aleve, Naprosyn), diclofenac (Voltaren), diflunisal (Dolobid), etodolac (Lodine), flurbiprofen (Ansaid), indomethacin (Indocin), ketoprofen (Orudis), ketorolac (Toradol), mefenamic acid (Ponstel), as well as Meloxicam (Mobic), Nabumetone (Relafen), Piroxicam (Feldene), and others.

Before you take this drug

It is not recommended to use Effient if you have an allergy to prasugrel or if you are:

  • Active bleeding, such as active bleeding such as a stomach ulcer or bleeding within the head (such as caused by an accident to the head);
  • A history of strokes, which includes tia ("mini-stroke"), the term used to describe strokes;
  • If you're planning to undergo surgery, particularly coronary bypass surgeries (coronary bypass grafts for arteries, also known as cabg),

To ensure that Efficient is suitable for you, inform your doctor if you have ever experienced:

  • A stomach ulcer, colon polyps, or diversioniculosis;
  • Bleeding issues;
  • Surgery, injury, or medical emergency
  • Kidney or liver disease;
  • If you're allergic to Clopidogrel or ticlopidine
  • If you weigh less than 130 pounds (60 kilograms), (60 kilograms) or less
  • If you're also using other medications to prevent or treat blood clots,

Inform your doctor if you are nursing or pregnant.

Similar/related drugs

Lisinopril, metoprolol, aspirin, clopidogrel, Plavix, ticagrelor, and pravastatin

How to be Effient?

Use Effient according to the prescription given by your physician. Follow the directions on your prescription label, and go through all medication guides and instructions sheets. If you take aspirin, be sure to follow your doctor's instructions regarding how much you should take and for how long.Effient can be consumed with and without meals.Suck the tablet completely, and make sure you don't chew, crush, or break it.Because Effient prevents your blood from bleeding, this medicine can cause you to be bleeding from a minor ailment. Seek emergency medical treatment if you are experiencing bleeding that won't stop.Speak to your physician about any planned procedure or dental work.Don't stop taking Effient without consulting your doctor, even if you feel well. If you stop taking this medication too soon, it can increase the chance of developing a blood clot, a heart attack, or even death.Keep Effient in a cool, dry place far from heat and moisture. Store the tablets in their original containers together with the packet or container of preservative that absorbs moisture.

Details on dosage

Usual Adult Dose of Effectiveness for Acute Coronary Syndrome:

Initial dosage: 60 mg taken orally, once
Dosage for maintenance 10 mg, orally at least once per day
No clear benefit was seen for the dose that was given prior to the diagnostic coronary angiography as compared to percutaneous coronary interventions (PCI). However, bleeding risk was elevated with the early administration of the drug in patients taking PCI or an earlier procedure for coronary artery bypass (CABG).
Aspirin 75–325 mg daily is recommended in conjunction with this medication.
Use: To lower the incidence of thrombotic cardiac events (including stent thrombosis) for patients with acute coronary syndrome (ACS) who need to be treated using PCI in the treatment of unstable angina (UA).Non-ST segment elevation myocardial infarction (NSTEMI) and ST segment elevation myocardial infarction (STEMI) can both lead to myocardial damage.

Usual Geriatric Dose of Efficacy for Acute Coronary Syndrome:

From 65 to less than 75:
The initial dose is 60 mg, once orally.
Dose for maintenance 10 mg taken orally, every day, once
75 years old or older: It is generally not recommended for patients who are 75 years of age or older for any reason, except in extremely risky circumstances (e.g., diabetes, or a prior myocardial infarction) in cases where risk is outweighed by benefit.
No clear benefit was seen for the dose that was given prior to the time of diagnostic coronary angiography as compared to percutaneous coronary interventions (PCI); however, the risk of bleeding was elevated with earlier administration of the drug in patients undergoing PCI or an earlier coronary artery bypass procedure (CABG).
Aspirin 75–325 mg daily is recommended in conjunction with this medication.
Use: To decrease the risk of thrombotic cardiovascular events (including stent bleeding) for patients suffering from acute coronary syndrome (ACS) who must be treated using PCI to treat unsteady angina (UA), non-ST segment elevation myocardial infarction (NSTEMI), and ST segment elevation myocardial ischemia (STEMI).

What happens if I miss the dose?

You should take the medication as quickly as you are able, but do not take any missed doses if you are nearing the time to take the next dose. Avoid taking two doses at the same time.

What happens if I overdose?

Get medical attention in an emergency or contact the poison help line at 1-800-222-1222.

What should be avoided?

Avoid activities that could increase the chances of sustaining injuries or bleeding. Be extra careful when shaving or scrubbing your teeth.Talk to your physician prior to using a nonsteroidal anti-inflammatory medication (NSAID) like naproxen, aspirin, ibuprofen, Advil, Aleve, Motrin, and many more. Utilizing an NSAID using Effient could cause bleeding or bruises easily.

Interaction with other drugs

Inform your physician of all of the medications you are currently taking, such as:

  • Opioid medications, also known as
  • Any other medications to prevent or treat blood clots. This includes heparin as well as warfarin (Coumadin, Jantoven).

This list isn't complete. Other medications can be incompatible with prasugrel, such as prescription and over-the-counter medicines, vitamins, and herbal products. There are many possible interactions between drugs. are listed here.



Prescription only

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