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Generic name: ethacrynic acid Etch-aKRIN-ik-AS-id]

Drug class: diuretics

What is Edecrin?

Edecrin can be described as a loop diuretic (water pill), which prevents your body from taking in too much salt. This allows the salt to be absorbed by urine.Edecrin can be used to treat liquid retention (edema) in patients suffering from liver or kidney conditions such as nephrotic disorders.Edecrin can also be used for reasons not mentioned in this medication guide.

Side effects of Edecrin?

Contact a medical professional immediately. If you are experiencing symptoms that indicate an allergic reaction, such as hives, difficulty breathing, or swelling of your lips, face, tongue, throat, or face,

Edecrin may cause serious side effects. Consult your doctor immediately in the event that you experience:

  • weight loss;

  • watery or severe diarrhea that is watery or severe;

  • hearing issues, feeling of a ringing in your ear;

  • Muscle cramps, severe weakness, and tingling or numbness

  • Feeling lightheaded as though about to faint.
  • Numbness or weakness that suddenly occurs in speech, difficulty with balance, chest pains, and coughing up blood

  • Low

    potassium: leg cramps, constipation, irregular heartbeats, fluttering of your chest, more frequent urination, or thirst Tingling or numbness causes muscles to become weak, sluggish, 

  • low sodium—headache and confusion. It can also cause slurred speech, extreme fatigue, vomiting, a lack of coordination, and feeling unstable.

Common side effects of the drug Edecrin can include:

  • discomfort, nausea, diarrhea, vomiting, or any other stomach pain;

  • Trouble swallowing

  • Loss of appetite

  • blurred vision

  • fever chills;

  • fatigue, headache.

This list does not represent an exhaustive listing of potential side effects; others could occur and should be discussed with your healthcare provider or reported to FDA at 1-800-FDA-1088 for investigation.


Do not take Edecrin if you're not able to urinate or if you've recently suffered from severe watery diarrhea.

Prior to use this drug 

Do not take Edecrin if you are allergic to it, or:

  • It is impossible to urinate

  • If you've recently experienced severe diarrhea with water,

To ensure that Edecrin is suitable for you, inform your physician if you suffer from:

  • Cirrhosis or another liver disease

  • Heart disease;

  • An electrolyte imbalance (such as low concentrations of magnesium, potassium, or magnesium in the blood);

  • kidney disease;

  • Gout

  • If you're following an e-diet that is low in salt,

Edecrin is not believed to harm the unborn baby. Consult your physician if you are expecting or planning to have a baby while using Edecrin.It isn't known if ethacrynic acid gets into breast milk or if it is harmful to the nursing infant. It is not recommended to breastfeed while taking this medicine.Edecrin is not a product that has been approved for use by anyone less than 18 years of age.

How to take Edecrin?

Follow the directions on the prescription label. Your doctor may change the dosage to ensure you receive the most effective outcomes. Avoid using this medicine in greater or lesser quantities or for a longer period than the recommended time.You should take this medicine after eating, unless your doctor advises you otherwise.Edecrin can cause you to frequently urinate, and you could become dehydrated quite easily. Follow the instructions of your physician about taking potassium supplements or ensuring that you get enough potassium and sodium from your food.When you are using Edecrin, it is possible that you might require regular blood tests and weight tests.Keep the bottle at room temperature, free of heat and moisture. Close the bottle when not being used.

What happens if I miss the dose?

Do the dose you missed as quickly as you can remember. Do not take extra medication in an effort to make up for a missed dose.Don't take any extra medication to make up for the missed dose.

What happens if I overdose?

Get medical attention in an emergency or contact the Poison Help Line toll-free at 1-800-222-1222.The symptoms of an overdose can consist of a dry mouth as well as increased thirst, mood swings, confusion or ringing in the ears, nausea, diarrhea, muscle pain or weakness, a lack of energy, rapid heartbeats, and a lack of or any urination.

What should be avoided?

Be sure to avoid becoming dehydrated. Follow the instructions of your physician regarding the amount and type of fluids that you must drink when you take Edecrin.

Interaction with other drugs

Discuss with your physician your current medications and any new medications you begin or stop taking, particularly:

  • digoxin, digitalis;

  • lithium;

  • blood pressure medication;

  • An antibiotic (including those administered via an IV);

  • A blood thinner—Warfarin, Coumadin, Jantoven;

  • The NSAIDs (nonsteroidal anti-inflammatory drugs): aspirin, Ibuprofen, aspirin (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac (also known as indomethacin), diclofe, and many others;

  • steroid medicine—prednisone, dexamethasone, and others.

This list isn't complete. Other medications can be incompatible with ethacrynic acid, which includes prescription and over-the-counter medicines, vitamins, and herbal supplements. There are many possible interactions that are not included in this guide to medication.



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