What is Depo-Estradiol?
The female hormone estradiol, also known as depo, regulates many bodily processes. The injection of Depo Estradiol is prescribed to relieve certain menopause symptoms, such as hot flashes or vaginal dryness. It can also be used for irritation, burning, and other side effects. The injection is used for a lack of estrogen caused by an ovarian problem, or hypogonadism. Depo-estradiol is used to treat symptoms of prostate cancer in men. Depo-estradiol only treats the symptoms, not the actual cancer. This medication guide does not list all possible uses of Depo Estradiol Injection.
Side effects of Depo-Estradiol
If you experience symptoms such as difficulty breathing, hives or swelling in your lips, face, throat or tongue that suggest allergies - difficulty in taking deep breaths; swelling of lips, face or throat (puffiness); difficulty with swallowing food etc - an allergy diagnosis should be immediately sought out and managed accordingly.
Depo-estradiol may cause serious side effects. If you experience:
- Heart attack symptoms include chest pressure or pain, spreading pain to the jaw or shoulder area, nausea, and sweating.
- Signs of stroke: sudden numbness, weakness, or headache (particularly on one side), slurred or shaky speech, or problems with balance or vision;
- Signs of blood clots include sudden vision loss, chest pain that pierces deep within, shortness of breath, blood in your cough or pain or heat in both legs.
- You may experience swelling in the stomach or feel tender.
- Jaundice is a yellowing of the skin and eyes.
- Memory problems, confusion, and unusual behaviors;
- Unusual vaginal bleeding and pelvic pain
- A lump on your breast
- High levels of calcium are accompanied by nausea, vomiting, diarrhea, and increased thirst. Other symptoms include muscle weakness, pain in the bones, fatigue, or a lack of energy.
Depo-estradiol can cause a number of side effects.
- Breast pain
- Headache;
- Breakthrough bleeding, vaginal discharge or itching, changes to your period,
- Hair loss on the scalp
- Nausea, vomiting, bloating, and stomach cramps.
There may be other side effects.Call your doctor if experiencing side effects; report adverse events by calling the FDA directly at 1-800-FDA-1088.
Similar/related drugs
Estradiol, Premarin, Estrace, Prempro, Norethindrone/ethinyl esteradiol, conjugated estrogens, ethinyl estradiol
Warnings
Do not take Depo Estradiol in the event that you suffer from undiagnosed vaginal bleeding, liver disease, or have had or will undergo major surgery. Avoid using it if pregnant. Depo-estradiol can increase the risk that you develop a condition that may result in uterine carcinoma. Do not ignore any abnormal vaginal bleeding. Depo-estradiol is not recommended to treat stroke or dementia.
Before you take this drug
Depo-Estradiol should be avoided if:
- Unusual vaginal bleeding not checked by your doctor
- Liver disease
- A history of stroke, heart attack, or blood clot
- A history of cancers of the breast, uterus, cervix, or vagina
Avoid using depo estradiol while pregnant. Inform your doctor immediately if a pregnancy occurs during treatment. Depo-estradiol increases your chances of having a stroke or heart attack. If you suffer from diabetes, elevated cholesterol, or obesity, you may be at greater risk.
This medicine can actually raise your chances of getting heart disease, stroke, or dementia.
If you've ever:
- Heart disease
- If you are pregnant or using hormones, it can cause liver damage or jaundice.
- A thyroid condition;
- Gallbladder Disease
- Kidney disease
- Asthma;
- Epilepsy and other seizure disorders
- Migraine headaches
- Lupus;
- Porphyria is a disorder of the genetic enzyme that can cause symptoms in the skin and nervous system.
- Endometriosis or uterine fibroid tumors;
- Calcium levels in the blood can be high or low.
- Hereditary Angioedema
Depo-estradiol can increase the risk of breast cancer, uterine cancer, and ovarian or ovaries cancer. Talk with your physician regarding this potential opportunity. Depo-estradiol may slow down the production of breast milk. Inform your doctor that you are breastfeeding.
How to take Depo-Estradiol?
Read all of the instructions or guides included with your medication and follow all directions precisely. Follow the directions on your prescription label. In general, depo-estradiol injections are given every two to four weeks, depending on the treatment. You can learn how to use this medication properly by consulting a healthcare professional. Please read and heed all directions that accompany your medication carefully. Depo-estradiol should not be used if the instructions are unclear. If you have any questions, ask your pharmacist or doctor. Only prepare your injection when you're ready to administer it. If the color of your medicine changes or if it contains particles, do not use it. For new medication, call your pharmacist. The use of depoestradiol can increase the risk that you will develop a condition that could lead to uterine carcinoma. A progestin may be prescribed by your doctor to lower the risk. Any unusual bleeding in the vaginal area should be reported immediately. Your doctor should periodically evaluate whether this treatment should continue. Furthermore, self-exams for lumps in your breasts should take place monthly as well as regular mammograms while taking Depo Estradiol. Keep heat and moisture at an acceptable room temperature at bay. Only use needles or syringes once, placing them immediately into your "Sharps Container." Follow local or state regulations regarding how you must dispose of this container - keep out of reach from children, pets and the general public!
What happens if I miss the dose?
If you missed your Depo Depo Estradiol appointment, call your doctor to get instructions.
What happens if I overdose?
Reach out immediately if a poison threat exists by dialling 1-800-222-1222 for assistance, or seek immediate medical attention.
What should be avoided?
Smoking is harmful. Depo-estradiol can increase the risk of stroke or heart attack. Grapefruit can cause unwanted effects when combined with depo-estradiol.Use as few grapefruit-based products as possible.
Interaction with other drug
It is sometimes not safe to take certain drugs at the same time. Some medications can cause side effects that increase or decrease the effectiveness of another drug you are taking. Depo Estradiol can be affected by other drugs, such as prescription, over-the-counter, herbal, or other products. Inform your doctor of all the medicines you are currently taking and those that you will begin or stop.
