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What is Demadex?

Demadex is an effervescent loop diuretic (water pill) that is prescribed for treating water retention (edema) in people suffering from heart disease, liver disease, or kidney disease. Demadex can also be employed to help treat hypertension. The reduction in blood pressure could reduce the risk of suffering a stroke or heart attack. Demadex can also be employed for other purposes that are not covered in this guideline.

Side effects of Demadex

See a doctor immediately. Get medical attention immediately if you notice symptoms or warning signs of an allergic response, like hives, trouble breathing, or swelling of your lips, face, and tongue.

See your doctor as soon as possible. If you suffer from:

  • A feeling of lightheadedness, as if you're passing out;
  • Ringing in your ears, the sudden loss of hearing
  • Kidney issues: little or no urine, pain or difficulty with urine, swelling of your ankles or feet, and feeling tired or weak;
  • Low magnesium level, causing dizziness and irregular heartbeats. Feeling anxious, muscle cramps, muscular spasms, coughing, or choking sensations
  • Lower potassium level: leg cramps, constipation irregular heartbeats chest fluttering, more frequent urination, or thirst Tingling or numbness, muscular weakness, a limp sensation,
  • Low sodium levels low sodium level—headache and confusion. It can also cause slurred speech, extreme weakness, vomiting, and a lack of coordination. Feeling unsteady.

Common negative effects of Demadex could include:

  • More frequent urination

This isn't a complete list of possible side effects, and other side effects could occur. Contact your doctor to seek medical advice on adverse effects. You can report any side effects to the FDA at 1-800-FDA-1088.

Similar/related drugs

Amlodipine, lisinopril, metoprolol, losartan, furosemide, carvedilol, and hydrochlorothiazide


It is not recommended to make use of Demadex if you are intolerant of sulfa medications or in the event that you are incapable of urinating.

Before you take this drug

Do not take Demadex if your body is allergic to it, or:

  • You aren't able to urinate or
  • You are allergic to orally administered diabetes

Speak to your doctor if you have ever suffered from:

  • Coronary disease;
  • Kidney issues (unless the medication you're taking is demadex for edema due to kidney problems);
  • Liver issues, such as liver problems like cirrhosis or hepatitis (unless you're taking demadex to treat the edema that is caused by an underlying liver condition);
  • Gout;
  • An allergy to the povidone (sometimes found in the iodine, betadine) as well as
  • If you're following an e-diet that is low in salt,

If you require any kind of x-ray or CT scan with the injection of a dye into your veins, your medical professionals recommend that you use Demadex.

Consult your doctor if you are expecting or planning to be pregnant. It isn't known if Demadex could harm the unborn baby. But having a high blood pressure during pregnancy could lead to complications like eclampsia or diabetes (dangerously high hypertension that could cause medical issues for both the baby and the mother). The advantages of treating hypertension can outweigh the risks for the baby. It might not be safe to breastfeed while taking this medication. Consult your physician about any potential risks. Demadex is not recommended for use by anyone less than 18 years old.

How to take Demadex?

Follow all the instructions on your prescription label, and review all medication guides and instructions. Your doctor might alter your dosage. Make sure you take the medication precisely as directed. Demadex oral medication is administered by mouth. Demadex injections are given in the form of an injection into the vein. Healthcare professionals can teach you how to use the medication on your own. This injection of medicine is given in a slow or steady infusion that lasts for 2 minutes or as a continuous (around the time) infusion.

If you suffer from cirrhosis or any other liver issues, You may be able to get an initial treatment in the clinic or in a hospital setting to treat any severe complications. Be sure to read and adhere to any instructions for use that are included in your medication. Consult your physician or pharmacist for clarification if you aren't sure about the instructions.

Make an injection only once you're ready to administer it. Avoid using any medicine that has changed color or contains particles. Contact your pharmacist to inquire about a new medication. You can take Demadex in combination with or without food. blood may be tested in the event that you've been vomiting or dehydrated.

Certain conditions may cause your blood pressure to become too low. This could include diarrhea, vomiting diarrhea, or excessive sweating. Consult your physician if you are suffering from vomiting or diarrhea. Your medical condition could be treated using an array of drugs. Take all medications as instructed by your physician. Do not alter your dosage or your medication schedule without a doctor's approval.

If you suffer from hypertension, continue taking Demadex orally, even if you are feeling well. The presence of high blood pressure is often accompanied by no indication. It is possible that you will need medication for blood pressure throughout your life. Keep it at room temperature, free of heat and moisture.

Do I be concerned if I miss a dose?

Do not take the medicine for as long as you can. However, do not take your missed dose if it's nearing the time to take the next dose. Don't have two doses at one time.

Contact your physician for advice in case you missed the dose of demadex injectable.

What will happen if I take excessively?

For medical emergencies, seek emergency medical attention or contact for help at the Poison Help Line at 1-800-222-1222.

Some symptoms of overdose consist of dehydration or unbalanced electrolytes (such as low concentrations of magnesium, potassium, and sodium in the blood) or the presence of low blood pressure and fainting.

What should be avoided?

Beware of becoming dehydrated or overheated when you exercise, during hot weather, or simply by having a deficiency in fluids. Follow the instructions of your physician regarding the types and amounts of liquids you must consume. In certain instances, drinking too much fluid could be as dangerous as drinking too little.

Interaction with other drugs

Discuss with your doctor the medicines you are currently taking. Certain drugs can interact with Demadex, specifically:

  • Any other diuretic medication;
  • Cholestyramine and lithium; phenytoin probenecid; rifampin warfarin (coumadin, jantoven);
  • Intravenous (iv) antibiotic medicine;
  • Antifungal medicine: fluconazole, miconazole;
  • Heart or blood pressure medicine—amiodarone, dronedarone, enalapril, irbesartan, lisinopril, losartan, olmesartan, valsartan, and others;
  • The nsaids (nonsteroidal anti-inflammatory drugs): ibuprofen (advil, motrin), naproxen (aleve), celecoxib, diclofenac, indomethacin, meloxicam, and more
  • Salicylates: aspirin, nuprin backache caplet, kaopectate, kneerelief, pamprin cramp formula, pepto-bismol, tricosal, trilisate, and others
  • Steroid medicine—dexamethasone, oxandrolone, prednisone, and others.

This isn't a complete list, and a variety of other medications could impact Demadex. This includes prescription and over-the-counter medications, vitamins, and herbal supplements. The interactions of all drugs are listed here.