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Generic name: glycopyrrolate (GLY koe PIE roe late) [GLY-koe-PIE-roe-late]
The class of drugs: anticholinergics and antispasmodics

What is Cuvposa?

Cuvposa is a member of a class of drugs referred to as anticholinergics. Cuvposa blocks acetylcholine receptors, which are found in specific organs within the body, such as the salivary glands. Glycopyrrolate can reduce the amount of saliva produced by preventing the stimulation of these receptors.

Cuvposa can be used to decrease the amount of salivation in children from 3 to 16 years old who have specific medical conditions, like cerebral palsy.


It is not recommended to use Cuvposa in the event of urinary problems or blockages in the stomach or intestines, serious constipation, serious ulcerative colitis, toxic megacolon, glaucoma, myasthenia gravis, or active bleeding due to issues with blood circulation or the heart.

Before taking Cuvposa, inform your doctor that you suffer from heart disease, kidney disease, a heart rhythm problem, a stomach condition, a colostomy, an ileostomy, a thyroid problem, high blood pressure, vision issues, numbness, or the sensation of tingling.

Prior to use this drug

Cuvposa is not recommended for use in the event that you are allergic to glycopyrrolate or you are:

  • A bladder obstruction or any other urinary problems;
  • An upset stomach or an obstruction in the bowel (including paralytic ileus);
  • Severe constipation that is severe;
  • Extremely ulcerative colitis or toxic megacolon
  • Glaucoma;
  • Myasthenia gravis; or
  • Active bleeding, with rapid beats of the heart, lower blood pressure, breath shortness, and cold hands or feet

To ensure that cuvposa is suitable for you, ask your doctor if you have ever experienced:

  • Increased prostate;
  • Kidney or liver disease;
  • Heart issues or a rhythm disorder
  • high blood pressure;
  • A stomach-related disorder like ulcerative colonic colitis, hiatal hernia, reflux disease, or slow digestion
  • A colostomy or ileostomy;
  • A thyroid disorder
  • A nerve disorder.

It isn't known if this medicine could cause harm to a baby who is not yet born. Inform your doctor if you are expecting or planning to be pregnant.

It is not recommended to breastfeed while taking Cuvposa. Glycopyrrolate could cause a decrease in breast milk production.

Avoid giving this medication to a child unless you have medical guidance.

How to take Cuvposa?

Utilize Cuvposa precisely as directed by your physician. Follow the directions on the prescription label and go through all medication guides and instructions sheets. The doctor might modify your dosage.

It is possible to drink Cuvposa on an empty stomach for a minimum of 1 hour prior to or 2 hours following eating. Follow the directions that come on the label of your medicine.

Make sure to measure the liquid medicine with care. Make use of the dosing syringe supplied or a dosage-measuring device (not the kitchen spoon).

Allow the tablet to disintegrate in the mouth without chewing. Drink the tablet with no water.

Glycopyrrolate dosages are determined by the weight of children. The dosage requirements for your child may alter if your child gains or sheds pounds.

Keep the bottle at room temperature, free of heat and moisture. Make sure the bottle is tightly sealed when not being used.

Details on dosage

Usual Pediatric Dose for Excessive Salivation:

1 mg/5 mL oral liquid for children ages 3 to 16 years old:
The dose to start is 0.02 mg/kg orally three times per day, at a minimum of one hour prior to and two hours after eating.
The dose is incremented by 0.02 mg/kg once every five to seven days, depending on reactions and adverse reactions.
Dosage maximum: 0.1 mg/kg three times per day, but not exceeding 1.5 to 3 mg per dose, based on weight.

Use: To limit excessive and severe drooling for patients ranging in age from 3 to 16 who suffer from conditions related to a problem with drooling (e.g., cerebral palsy).

What happens if I miss a dose?

You should take the medication as quickly as you can. However, avoid any missed doses if you are close to the time of the next dose. Don't have two doses at one time.

What happens if I overdose?

Get medical attention in an emergency or contact the poison help line at 1-800-222-1222.

Overdose symptoms can include severe muscle weakness and loss of movement. Other symptoms include dilation of the pupils, jerky muscle movements, and seizures (convulsions).

What should be avoided?

Avoid driving or engaging in hazardous activities until you are aware of the effects of this medication on your body. The way you react could be impaired.

Beware of becoming dehydrated or overheated when exercising and during hot temperatures. Cuvposa reduces sweating and increases your risk of becoming susceptible to suffering from heat stroke.

Consuming alcohol while taking this medication could cause adverse consequences.

Side effects of Cuvposa

Take immediate medical attention. If you are experiencing symptoms of an allergic reaction, Cuvposa symptoms include difficulty breathing, hives, and swelling of your lips, face, or tongue.

Stop taking Cuvposa and contact your doctor immediately if you suffer from:

  • Extreme constipation, abdominal pain, and even bloating
  • Diarrhea (especially when you have a colostomy or ileostomy);
  • Uncomfortable or difficult to urinate;
  • Heartbeats that are fast or rapid; the heart beating fast;
  • Confusion, severe drowsiness,
  • Eye pain, seeing halos around lights;
  • Rapid breathing, weak pulse, red and hot skin,
  • (in children who are Cuvposa): dry diapers, headaches, or crying too much.

Common Cuvposa side effects can include:

  • Constipation, nausea, vomiting, and bloating;
  • Drowsiness, dizziness, weakness, feeling nervous;
  • Rapid or slow heartbeats;
  • Sleep problems (insomnia);
  • Flushing (sudden heat, redness, or tingly sensation);
  • Vision blurred, sensitivities light
  • Dry mouth, reduced sense of taste
  • Reduced sweating, decreased the frequency of urination,
  • Impotence and sexual problems
  • Headache

This is not a comprehensive list of all side effects. Other side effects could occur. Contact your doctor for advice regarding medical effects. You may report any adverse reactions to the FDA at 1-800-FDA-1088.

Interaction with other drugs

There are times when it's not recommended to take certain medications simultaneously. Certain drugs may affect the blood levels of other medications you are taking, which could create side effects or render the medication less effective.

Inform your doctor about any other medications you take, including:

  • Medications for treating the symptoms of depression, anxiety, mood disorders, depression, or mental illness
  • Opioid medications;
  • Sleep medicine as well as allergy and col d medicines (Benadryl and others);
  • Medication for treating the symptoms of Parkinson's disease;
  • Medicine to treat stomach disorders, motion sickness, and IBS;
  • Medicine to treat the symptoms of an overactive bladder;
  • The bronchodilator asthma medicine o
  • Seizure medication.

This list is not comprehensive. Other medications may be incompatible with glycopyrrolate, such as prescription and over-the-counter medicines, vitamins, and herbal products. Some interactions with drugs are not listed here. are listed here.