What is Carimune (IGIV)?
Intravenous immunoglobulin is used for the treatment of primary immune deficiency. IGIV can also be used to increase the number of platelets (blood clotting cells) in patients with immune thrombocytopenic purpura. IGIV can also be used to prevent certain infections among people with B-cell chronic lymphocytic leukaemia. IGIV can also be used to treat Kawasaki syndrome, a condition where the main artery of the heart weakens. This causes aneurysms. IGIV can be used in other ways not mentioned in this guide.
Side effects of Carimune (IGIV)
If you experience any of the following signs and symptoms of an allergic reaction: difficulty breathing, hives or any swelling on lips, face or throat - seek medical assistance immediately! Some side effects can occur during the injection. You should tell your carer if your symptoms include feeling dizzy, lightheaded, nauseated, or sweaty.
Carimune may cause serious side effects. If you experience:
- A blood cell disorder: pale, yellowed, or dark urine; fever or confusion;
- Dehydration symptoms—feeling thirsty, hot, or unable to urinate. Heavy sweating or hot and dried skin.
- Kidney problems: swelling, weight gain, shortness of breath, little or no urine,
- Blue lips, toes, or fingers are signs of lung problems.
- Signs of a new infection include a fever with a severe headache, a stiff neck, eye pain, and increased sensitivity.
- Signs of a blood clot include shortness of breath, chest pain when deep breathing is done, rapid heartbeat, numbness on one side, swelling, warmth, or discoloration of an arm or leg.
Carimune can cause the following side effects:
- Headache, joint, or muscle pain.
- Fever, chills, or sweating
- Diarrhoea, and stomach pain.
- Increased blood pressure and rapid heartbeats
- Dizziness, fatigue, and lack of energy are all symptoms that can be experienced.
- Stuffy nose, sinus pain,
- Pain, swelling, irritation, or burning around the IV needle
There may be other side effects. Call your physician if experiencing side effects; alternatively, the FDA can be reached at 1-800-FDA-1088 if necessary to report these.
Warnings
Carimune may cause blood clots. The risk is higher in older adults, people with heart disease, blood circulation issues, and those who have previously had blood clots. Blood clots can also occur during prolonged bed rest, when using birth-control pills, hormone replacement therapy, or having an IV catheter.
If you experience chest pain, difficulty breathing, rapid heartbeats or numbness, weakness, or swelling in your arm or leg, as well as warmth and discoloration, call your doctor immediately.
This medication can also damage your kidneys. Especially if you are suffering from kidney disease or if you take certain medications. If you notice any symptoms of kidney disease, such as swelling, rapid weight gain, or little to no urination, tell your doctor immediately.
Before you take this drug
This medication may not be appropriate if any of the following apply to you:
- You have experienced an allergic reaction to immune globulins or blood products.
- You have an immune globulin A deficiency and antibodies to iga.
- You are allergic to corn.
IGIV may cause kidney or blood clot problems, particularly in older adults and people with certain medical conditions. You should tell your doctor if:
- Heart problems, blood circulation problems, or "thick blood";
- A blood clot or stroke
- Kidney disease
- Diabetes;
- Sepsis is an infection.
- If you use oestrogens (birth control pills or hormone replacement therapy),
- If you've been on bedrest for a long time,
- If you already have an intravenous central catheter (IV),
If you have been exposed to or are travelling to an area with a high prevalence of this disease, you may need to adjust your dose.
Inform your doctor if you are pregnant or nursing. The immune globulin made from human plasma can contain viruses and other infectious agents. Plasma is treated and tested to reduce the chance of contamination. However, there is still some risk. You should ask your doctor if there are any risks.
How to take Carimune (IGIV)?
IGIV is administered as an intravenous infusion, typically once every three to four weeks. This injection will be given by a healthcare provider. Carimune can help improve blood flow, which will keep your kidneys functioning properly. Blood or urine tests may be required frequently. It can also affect certain medical tests. Inform any doctor that treats you about your use of IGIV.
What happens if I miss the dose?
If you are unable to attend your appointment, call your doctor and ask for instructions.
What happens if I overdose?
Call 1-800-222-1222 for poison help or seek immediate medical attention.
What should be avoided?
Consult your doctor prior to receiving a “live” vaccine when using IGIV. It may not protect you as well or work as effectively. Live vaccines are available for measles (mumps), rubella, typhoid (typhoid fever), varicella (the chickenpox), or shingles (shingles).
Interaction with other drug
IGIV may harm your kidneys if you are also taking certain medications for cancer, cancer treatment, osteoporosis or organ rejection, bowel problems, high blood pressure, pain, arthritis, or other conditions (including Advil and Motrin). Other drugs, such as vitamins and herbal remedies, may also affect IGIV. Inform your doctor of all the medicines you are taking and those that you stop or start using.
