Cabozantinib

What is Cabozantinib?

Cabometyx can be used to treat advanced renal cancer. It is sometimes combined with another medication called Nivolumab. Cabometyx can also be used to treat liver cancer in people who have previously been treated with Sorafenib. Cabometyx is also used to treat thyroid cancer in people aged 12 and older. Cometriq treats thyroid cancer, which has spread to other areas of the body. Cabozantinib can be used in other ways not mentioned in this guide.

Side effects of Cabozantinib

If you experience any of the following signs and symptoms of an allergic reaction: hives, difficulty breathing and swelling of face, lips or throat Cabozantinib can cause a fistula or perforation in your stomach or intestines. If you experience severe stomach pain or feel as if your throat is closing up, call your doctor.

Cabozantinib may cause serious side effects. If you experience:

• Severe headache; blurred vision; or pounding in the neck and ears
• Severe and persistent symptoms of nausea or diarrhea;
• You may experience swelling of your hands, arms, or legs.
• Easy bruising and bleeding (nosebleeds, bleeding gums, heavy menstrual bleeding, or any bleeding that will not stop);
• Bloody or tarry stools; a cough that produces bloody mucus; or vomit that looks like coffee grounds.
• Jaundice
• Pain, blisters, or bleeding in your palms or soles
• Confusion, weakness, confusion, seizures, and thinking problems
• Feeling lightheaded as though they could faint.
• After dental treatment, you may experience jaw pain, numbness, or red gums. You may also notice loose teeth or slow healing.
• Low blood calcium—muscle spasms, contractions, numbness, or tingly feelings (around the mouth or your fingers and toes)
• Low white blood cells: fever; mouth sores or skin sores; sore neck; coughing; difficulty breathing.
• Adrenal gland problems: nausea, vomiting, extreme fatigue, dizziness, weakness, fainting
• Signs of a stroke and blood clot include sudden numbness, weakness, or difficulty speaking or understanding what you are being told; chest pain; breathing difficulties; or swelling in your arm or leg.

If you experience certain side effects, your future doses of Cabozantinib could be permanently stopped or delayed.

Cabozantinib can cause the following side effects:

• Tiredness, depression, thinning of hair, decreased perspiration, and weight gain Also, you may feel more sensitive to cold temperatures.
• Constipation, diarrhoea, nausea, stomach pain, and vomiting
• Pain, redness, swelling, or sores on your tongue or throat
• Trouble speaking is a change in taste.
• Cold symptoms, including stuffy noses, sneezings, sore throats, and coughing;
• Rash;
• Pain in your joints, muscles, or bones;
• Abnormal liver function tests and other blood tests
• Weight loss;
• Hair colour is changing to lighter.

There may be other side effects. Need medical advice about side effects? Make an appointment to speak to your physician now. The FDA can be contacted at 1-800-FDA-1088 to report side effects.

Similar/related drugs

Keytruda, Avastin, Armour Thyroid, Pembrolizumab, Nivolumab, Bevacizumab, and Doxorubicin

Warnings

Cabozantinib can cause a fistula or perforation in your stomach or intestines. Cabozantinib may also increase the risk of bleeding. If you experience severe abdominal pain, choking, tarry or bloody stools, unusual bleeding or bleeding that is not normal, heavy menstrual blood, or coughing up blood, call your doctor.

Before you take this drug

Tell your doctor if:

• Hypocalcemia; is defined as having low levels of calcium in your blood (hypocalcemia);
• An open wound (or one that is healing) on the skin;
• Bloody stools (such as tarry or bloody stools or vomiting blood or coffee grounds);
• High blood pressure
• Liver disease
• A pre-existing dental problem.

Before starting the treatment, you may need a negative pregnancy result. Cabozantinib can harm an unborn child. Prevent pregnancy by using effective contraception while taking cabozantinib and for 4 months following your last dose. If you suspect you may be pregnant, tell your doctor. Both men and women may be affected by this medicine. It is still important to use birth control to avoid pregnancy, as cabozantinib may harm the unborn child. This medicine should not be taken while breastfeeding or for at least four months after the last dose.

How to take Cabozantinib?

Read and follow all instructions or guides included with your medication.Sometimes, your doctor will change the dose. You must take the medication exactly as prescribed. Use cabozantinib pills only. Do not substitute cabozantinib tablets. Only take the form of pills prescribed by your doctor. Always check the medication you receive from the pharmacy to avoid any mistakes. Do not eat for at least an hour or two after taking cabozantinib. Take this medication without food. Take this medication with a glass of water. You should not break, crush, chew, or open a capsule. Swallow the entire pill. Nivolumab, when used in conjunction with Cabometyx, is typically given by vein injection every 2 to 4 weeks. You may need to check your thyroid and liver functions, as well as your blood pressure. Stop taking Cabozantinib 3 weeks before you need dental or surgery work. You may have to wait up to 2 weeks after a dental or surgical procedure before you can take cabozantinib. Do not neglect to follow your physician's advice and instructions. Talk to your doctor if you've stopped taking cabozantinib. Store away from heat and moisture at room temperature.

What happens if I miss the dose?

If you miss a dose, take it immediately. If possible. Skip the missed dose when your next dose is less than 12 hours away. Never take two doses of the same medicine at once.

What happens if I overdose?

Reach out immediately if a poison occurs by calling 1-800-222-1222 or seeking immediate medical care.

What should be avoided?

Grapefruit can interact with cabozantinib, causing unwanted side effects. Use grapefruit products sparingly while taking cabozantinib. St. John's wort is a dangerous herb. John's wort.

Interaction with other drug

It is sometimes not safe to take certain medications together. Some drugs may affect the blood levels of drugs that you are taking, which can increase side effects and make them less effective. Other drugs, such as vitamins and herbal remedies, may also affect cabozantinib. Inform your doctor of all the medicines you are currently taking and those that you will begin or stop using.