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Pronunciation: Bry-HAL-ee

Generic Name: Halobetasol propionate 0.01 percent.
Dosage Forms: Lotion.
Drug Class: Topical steroids.

Active Ingredients: Halobetasol Propionate, 0.01 percent.

Inactive Ingredients: carbomer copolymer types B as well as type A diethyl sebacate and edetate disodium light mineral oil, propylparaben, methylparaben sodium hydroxide, sorbitan monooleate, and sorbitol.

What is Bryhali?

Bryhali is a potent, Class I corticosteroid cream that can be utilized by adults to lessen the itching and inflammation that are due to plaque psoriasis. It is made up of 0.01 percent halobetasolpropionate. Bryhali has been approved by the FDA on November 6, 2018. It has a lower concentration than other halobetasol propionate creams, which reduces the chance of adverse consequences.


Follow the directions on the label of your medication and the package. Be sure to inform your health care providers about your allergies, medical conditions, and all medications you take.

Bryhali (halobetasol propionate 0.01% lotion) is a highly potent Class I corticosteroid that can be absorbed through the skin into the bloodstream and cause reversible hypothalamic-pituitary-adrenal (HPA) axis suppression with the potential for glucocorticosteroid insufficiency, including Cushing's syndrome, hyperglycemia, and glucosuria. Avoid using for more than 2 weeks, and limit your use to the dose recommended. Regular monitoring for HPA suppression might be necessary.

Before you take this drug

Halobetasol is not recommended for use topically if you're allergic to it. Bryhali is not recommended for lesions that release serum or on skin folds (where two areas of the skin meet).

Inform your doctor if you were ever diagnosed with:

  • Any skin condition.
  • The skin reacts to any medication that contains steroids.
  • Liver disease.
  • An adrenal gland disorder of the adrenal gland.

Topical corticosteroids may increase glucose (sugar) levels in urine or blood. Consult your physician if you are suffering from diabetes. Children are more vulnerable to systemic absorption of corticosteroids applied to the skin. Bryhali is not recommended for use by people younger than 18 years of age.

It isn't clear if topical halobetasol can affect a newborn baby. Inform your physician if you are expecting. If you're instructed to take Bryhali, make sure you only use one or two drops for as short a time as you can. It might not be safe to breastfeed while taking this medication. If you're advised to take Bryhali, make sure you only use one or two drops for the shortest amount of time. Don't apply it to your breasts.

How to take Bryhali?

Make sure you apply Bryhali exactly as directed by your physician. Follow the directions on the label of your prescription and study all medication guides or instruction sheets.

Do not consume the medication by mouth or apply it intravaginally. Topical medicines are for use solely on your skin. Don't apply it to burns that are open or on dry, sunburned, or irritated skin. Cleanse your face with water in the event that Bryhali is found in your mouth or eyes.

  • Cleanse your hands prior to and after applying Bryhali, except if you are using the medicine to treat skin problems on the hands.
  • Apply a thin layer of Bryhali lotion to the areas affected each day. Apply the lotion gently and thoroughly. Avoid applying this medication to a large area of your skin unless your physician has instructed you to.

Do not cover the affected skin region with a bandage or any other type of covering unless your physician has instructed you to. Covering areas that have been treated may boost the quantity of medication in your skin and could cause adverse side effects.

Bryhali lotion is intended for use for short periods only (up to eight weeks). Take care to follow your doctor's dosage directions. Clinical studies have proven that Bryhali remains effective in providing relief from psoriasis for as long as 4 weeks after being removed from your treatment.Contact your physician if your symptoms don't improve after 8 weeks or if they become worse. Do not use the medication in the event that your symptoms improve earlier.

What happens if I miss a dose?

Apply the product as fast as you are able, but do not take the dose you missed when it's almost time to take your next dose. Avoid taking two doses at the same time.

What happens if I overdose?

For medical emergencies, seek emergency treatment or contact the Poison Help line at 1-800-222-1222 if you have accidentally swallowed the medicine.

Prolonged or excessive usage of Bryhali lotion may result in thinning skin, easy bruising, shifts in body weight (especially on the neck, face, back, waist, and face), increased facial hair, acne, menstrual disorders, impotence, or losing interest in sex.

What should be avoided?

  • Do not apply Bryhali on your scalp, face, underarms, groin, or underarm areas. It is not recommended for the treatment of any skin issue that hasn't been examined by your doctor.
  • Do not apply other topical steroids to the areas where you apply Bryhali unless your physician tells you to.
  • Limit your consumption to 50 grams a week.

Adverse effects of Bryhali

See a doctor immediately. If you notice symptoms that indicate an allergy reaction, like hives, difficulty breathing, and swelling or redness of the lips, face, and tongue,

See your doctor right away. If you suffer from:

  • An increase in the severity of your skin conditions.
  • The appearance of redness, warmth, ousting, or extreme irritation on any skin treated.
  • Blurred vision, tunnel vision, eye pain, or seeing halos around light sources.
  • High blood sugar (more thirst, more frequent urination, dry mouth, odor of fruity breath.
  • Possible signs of absorption of the medicine through your skin, such as weight growth (especially on your face or the upper part of your back or torso), Slow healing of wounds, thin and discolored skin, an increase in the amount of body hair on your skin, weakness in muscles fatigue, nausea, diarrhea, mood changes, as well as sexual changes.

Common Bryhali side effects can be:

  • Upper respiratory tract infection.
  • Burning, itching, or dryness on the skin of those who have treated it.
  • High blood sugar levels.

Other adverse side effects that could result from topical corticosteroids are:

  • Acne.
  • Skin discoloration where the tape was placed.
  • Dryness.
  • Excessive hair growth.
  • Miliaria.
  • Cataracts and glaucoma are examples of ophthalmic side effects.
  • Contact dermatitis.
  • The appearance of a crust or redness around hair follicles (folliculitis).
  • Thin skin.
  • Spider veins.
  • Stretch marks.

Topical corticosteroids can cause reversible hypothalamic-pituitary-adrenal (HPA) axis suppression, with the potential for glucocorticosteroid insufficiency.If you get an infection on your skin while taking Bryhali, your doctor might prescribe an antimicrobial cream to use. If this is not enough to cure the issue, your doctor could stop Bryhali until your infection is gone.If irritation occurs, If irritation develops, discontinue the use of Bryhali.This is not an exhaustive list of all possible adverse effects. Other side effects could occur. Contact your doctor to seek medical advice on adverse effects. You can report adverse reactions to the FDA at 1-800-FDA-1088.

Interaction with other drugs

Bryhali is not likely to interact with other drugs you use. But it is not recommended to take it in conjunction with other oral or topical corticosteroids, as they could have an adverse impact. Discuss with your doctor the medicines you take, such as prescription and over-the-counter supplements, vitamins, and herbs.


Store at room temperature, 20°C, 25°C, or 20°C (68°F between 77 and 68°F). Don't freeze. Keep out of reach of children.