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Brilinta

Pronunciation: brih-LIN-tah
Generic Name: Ticagrelor
Drug Class: Platelet aggregation inhibitors

What is Brilinta?

Brilinta stops the blood platelets from clumping together to form a blood clot, which could stop an artery.Brilinta can reduce the chance of suffering from heart attacks or strokes, as well as death caused by an artery that is blocked or a previous heart attack.

Brilinta can also be utilized to reduce the chance of developing blood clots when you suffer from coronary artery disease (decreased coronary blood flow) and are treated with stents to clear clogged arteries.Brilinta can also be utilized to decrease the chance of suffering a stroke or heart attack if there is a reduction in blood flow to your heart.Brilinta also helps reduce the chance of death and stroke in people who suffer from blocked blood flow through an artery that delivers oxygen to the brain.This medication is usually administered in conjunction with aspirin at low doses. Be sure to follow your doctor's instructions. In excess of aspirin, it can reduce the effectiveness of ticagrelor.

Warnings

It is not recommended to use Brilinta in the event of active bleeding (including stomach ulcers that are bleeding) or a prior history of bleeding within the brain. Don't use this medication just prior to surgery to bypass the heart (coronary bypass graft for arteries, or CABG).

It is possible that you will have to stop taking this medication for a short period prior to getting dental or surgical work to stop bleeding excessively. Don't discontinue using Brilinta without first speaking to your doctor, even if you show symptoms of bleeding. Stopping this medicine could increase your chances of suffering an attack on your heart or stroke.Brilinta can cause bleeding to occur more frequently, and this can be serious or even life-threatening. Avoid activities that increase the chances of sustaining injuries or bleeding.Contact your doctor or seek urgent medical attention. If you are experiencing bleeding that won't stop, There may be bleeding in the interior of your body, for instance, within your stomach or intestines. Consult your physician immediately. If you notice bloody or black stools as well as pink or red urine or have a bloody spit-up or vomit that resembles coffee grounds, These are signs of internal bleeding.

Many medications (including certain over-the-counter medications or herbal supplements) could trigger serious medical issues if you use them together with Brilinta. It is crucial to inform your physician about every medication you've recently taken.

Before you take this drug

Brilinta is not recommended for use. Brilinta If you have an allergy to ticagrelor or you are:

  • Any active bleeding.
  • The history of bleeding in the brain (such as the result of a brain injury).

Inform your doctor if you were ever diagnosed with:

  • A stroke.
  • Heart issues.
  • High cholesterol.
  • Bleeding issues.
  • A stomach ulcer or colon polyps.
  • Liver disease.
  • Kidney disease.
  • Asthma, COPD (chronic obstructive pulmonary disorder), or any other breathing issues.
  • Recent surgeries or injuries.
  • If you're contemplating having surgery or undergoing a dental procedure.

It is still unknown if this medication will affect a newborn baby or not. Inform your doctor if you are expecting or planning to be pregnant. It isn't known if Brilinta gets into breastmilk. Discuss with your physician before taking Brilinta when you breastfeed.

How to take Brilinta?

Use Brilinta exactly as directed by your physician. Follow the instructions on your prescription label and go through all medication guides or instruction sheets. Brilinta is taken along with aspirin. Take these medications exactly according to the directions.Do not use more aspirin than your doctor has advised. Taking too much aspirin may make Brilinta less efficient.You should take this medication every day, either with or without meals.

If you can't take a tablet completely, crush it, then mix the crushed tablet with water. Mix and drink this mix immediately. Add additional drinking water, mix, and then drink immediately.Brilinta stops blood from getting coagulated (clotting) and could make it more difficult for bleeding, even after a minor injury. Consult your physician or seek urgent medical attention in the event of bleeding that won't stop.To stop bleeding excessively, it is possible to stop taking Brilinta for a brief period prior to any surgery, medical procedure, or dental procedure. Any doctor who cares for you must know that you're taking ticagrelor. Stop taking Brilinta without first speaking to your physician, regardless of the symptoms that indicate that you are bleeding. Stopping the medicine can increase the chances of having a stroke or heart attack.

Ticagrelor can affect the medical tests to determine the amount of platelets present in your blood, and it is possible to get false results. Inform the laboratory personnel that you are using Brilinta. Keep at room temperature, free of heat and moisture.

Details on dosage.

Usual Adult Dose for Acute Coronary Syndrome:

In the aftermath of the acute coronary syndrome (ACS) incident:
Dose of loading: 180 mg taken orally once
Maintenance dosage: 90 mg orally every day, twice per day for 1 year
Maintenance dose after one year: 60 mg taken orally twice daily.
Comments: This medication should be taken together with a dose of 75–100 mg of aspirin taken orally every day.
For at least the initial 12 months after ACS, this medication is superior to clopidogrel for the first 12 months following ACS.
Uses: To decrease the incidence of death from cardiovascular causes as well as myocardial infarction and stroke among patients suffering from the acute coronary syndrome (ACS) or a history of myocardial injury.
to reduce the incidence of stent thrombosis among patients who have had stents to treat ACS.

Usual Adult Dose for Prevention of Atherothrombotic Events:

In the aftermath of the occurrence of an acute coronary syndrome (ACS) incident:
Dosage for loading: 180 mg taken orally once
Maintenance dose: 90 mg taken orally twice daily for one year
Maintenance dose after one year: 60 mg twice daily.
Comments:
This medication should be taken along with a daily dose of 75–100 mg once daily.
For at least the initial 12 months after ACS, this medication is superior to clopidogrel for the first 12 months following ACS.
Uses: To decrease the incidence of heart attack, myocardial infarction, and stroke among patients suffering from the acute coronary syndrome (ACS) or a history of myocardial infarction.
to reduce the incidence of thrombosis in stents among patients who have had stents to treat ACS.

Usual Adult Dose for Thromboembolic Stroke Prophylaxis:

60 mg taken orally twice per day
Use: To decrease the chance of having an initial myocardial infarction (MI) as well as a stroke among patients suffering from coronary artery diseases (CAD) with a high risk of these events. Although the use of this drug is not restricted to this particular situation, the effectiveness of this medication was demonstrated in a patient population suffering from the condition known as type 2 diabetes (T2DM).

Usual Adult Dose for Coronary Artery Disease:

60 mg orally, twice a day
Use: To decrease the likelihood of suffering the first myocardial injury (MI) as well as stroke among patients suffering from coronary arterial disease (CAD) who are at risk of such events. Although it isn't restricted to this situation, the efficacy of this drug has been established in a group of patients suffering from diabetes mellitus type 2 (T2DM).

Usual Adult Dose for Myocardial Infarction—Prophylaxis:

60 mg taken orally twice per day
Use: To lower the chance of having myocardial infarction (MI) as well as stroke among patients suffering from coronary arterial disease (CAD) with the highest risk of such incidents; however, the use of this drug is not restricted to this situation; the efficacy of this drug has been established in a group of patients suffering from the condition known as type 2 diabetes (T2DM).

What happens if I miss a dose?

Take the missed dose off and take your subsequent dose at the same time. Do not try to use two doses at the same time.

What happens if I overdose?

For medical emergencies, seek emergency medical attention or contact the Poison Help Line at 1-800-222-1222. The overdose could cause excessive bleeding.

What should be avoided?

If you drink alcohol and take aspirin, it increases the risk of bleeding in your stomach. Avoid activities that could increase the chance of injury or bleeding. Make sure you take extra precautions to prevent bleeding when shaving or brushing your teeth.

When taking Brilinta along with aspirin, you should avoid using medicines for swelling, pain, fever, or other cold or flu-like symptoms. These medicines may contain ingredients that are similar to aspirin (such as salicylates, ibuprofen, ketoprofen, or naproxen). Combining certain products could cause you to take too much aspirin and increase your chances of bleeding.

Side effects of Brilinta

See a doctor immediately. If you are experiencing symptoms for an allergy reaction, Brilinta: hives, breathing problems, and swelling of your lips, face, and tongue. See your doctor right away. If you are suffering from:

  • Chest pain.
  • Dizzy spells or fainting.
  • Nosebleeds and any other bleeding that does not stop.
  • Breath, even after light exertion or lying down.
  • Easily bleeding, unusual bruising, or the appearance of red or purple spots beneath the skin.
  • Either pink, red, or brown urine.
  • Bloody, black, or tarry stool.
  • Vomiting blood.

Common Brilinta adverse effects could include:

  • Bleeding.
  • Breathlessness.

Other side effects could occur. Contact your doctor for any advice regarding adverse effects. You may report any adverse reactions to the FDA at 1-800-FDA-1088.

Interaction with other drugs

It is sometimes not safe to take certain medicines simultaneously. Certain medications can alter the blood levels of other medications that you take, which can cause more side effects or make the drugs less effective.

Inform your doctor about your current medications. Certain medications are likely to interfere with Brilinta, specifically:

  • Antifungal medication (including itraconazole, ketoconazole, voriconazole, and many others).
  • Antibiotic medication (including clarithromycin).
  • Antiviral medication to treat HIV and AIDS.
  • Other blood thinners.
  • Cholesterol medication (including simvastatin or lovastatin).
  • Heart or blood pressure medication.
  • Opioid medication.
  • Seizure medicine.
  • Tuberculosis medicine (especially Rifampin).

This is not a complete list, and a variety of other medications could influence Brilinta. This covers prescription and OTC medications, vitamins, and herbal products. There are many possible interactions between drugs, which are included here.

DRUG STATUS

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Prescription only

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