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Aspirin and caffeine

Generic names: caffeine and aspirin
Brand names: include: Alka-Seltzer Hangover Relieve, Alka-Seltzer Morning Relief, Anacin, Anacin Extra Strength, Bayer Back and Body,… display the 14 brands
Forms of dosage: oral powder for reconstitution (1000 mg–65 mg; 845 mg–65 mg) Oral tablet (400 mg–32 mg; 421 mg–32 mg; 500 mg–32 mg; 500 mg–32.5 mg),… Show all three dosage forms.
Drug class: analgesic combinations

What is Aspirin and caffeine?

Aspirin, along with caffeine, is a salicylate (sa-LIS-il-ate). It is a drug that works by reducing the amount of substances within the body that trigger discomfort, fever, and inflammation.Caffeine is utilized in this product to boost the pain-relieving effects of caffeine and aspirin.Aspirin and caffeine are a mixed product that is used in treating migraines, muscle pain, mild arthritis-related pain, and fever, as well as bodyaches that are caused by the common cold. typical cold. Aspirin and caffeine are often used to combat heart attacks or prevent strokes and chest discomfort (angina). Aspirin and caffeine are recommended for heart conditions in conjunction with a physician.Aspirin and caffeine can be used to treat conditions not mentioned in this medication guide.

Side effects of Aspirin and caffeine

Contact a medical professional immediately if you notice any of the following symptoms that indicate an allergic reaction: hives; trouble breathing; and swelling of your lips, face, and tongue.

Aspirin and caffeine can produce serious side effects. Take a break from aspirin and caffeine, and consult your physician immediately if you suffer from:

  • A ringing sound in your ear; hearing ringing in your ears; confusion; hallucinations; seizures; rapid breathing (convulsions);
  • Severe nausea, vomiting, or stomach pain;
  • The stool is bloody or tarry and coughs up blood, or it looks similar to coffee grounds.
  • Fever that lasts longer than 3 days,
  • Stay alert for swelling or pain lasting more than 10 days, particularly if this persists for more than 7 days.

Common negative effects of aspirin or caffeine can include:

  • Uneasy stomach, heartburn;
  • Drowsiness
  • Mild headache that is mild.

This is not a comprehensive list of possible side effects, and other side effects could occur. Contact your physician for advice regarding medical effects. Please call 1-800-FDA-1088 if any side effects develop; their number can be found above.


Aspirin can cause bleeding from the stomach or in the intestinal tract that can lead to fatal bleeding.Aspirin is also known to cause extreme allergic reactions. Seek medical attention immediately when you experience an allergic reaction, wheezing, or swelling on your lips, face, and throat.Aspirin or caffeine should not be used if you suffer from an ongoing bleeding condition like hemophilia.Don't give this medication to a teenager or a child suffering from fevers, flu symptoms, or chicken pox. Aspirin is known to cause Reye's syndrome, a severe and often fatal condition for children.

Before you take this drug

This medicine if you're allergic to caffeine or aspirin, or if you suffer from

  • A recent experience of intestinal bleeding or stomach
  • Active bleeding triggered by hemophilia or a blood-clotting disorder, or
  • An allergic reaction to nsaids (nonsteroidal anti-inflammatory medications) like Advil, Motrin, Aleve, Orudis, Indocin, Lodine, Voltaren, Toradol, Mobic, Relafen, Feldene, and many others.

Do not give this medicine to a teenager or child suffering from the flu, fever symptoms, or chickenpox. Caffeine and aspirin could cause Reye's syndrome, a dangerous and sometimes fatal illness for children.This medication can cause bleeding in the stomach or intestines that can lead to death. These issues can happen at any time, without warning, if you're taking caffeine and aspirin in particular.

  • If you're 60 years old or older,
  • If you have a stomach ulcer or have a background of stomach or intestinal bleeding,
  • If you are taking a blood thinner (Warfarin, Coumadin) or steroid medication,
  • If you consume more than three alcohol-based drinks in a day,
  • If you are taking the medication for longer than the recommended time,

Speak with a physician or pharmacist to determine if it's safe to take this medication in the event of any other medical condition, particularly:

  • Any issues with stomach bleeding or a bleeding disorder;
  • The heart condition, high blood pressure;
  • Asthma or seasonal allergies
  • Kidney disease or liver failure;
  • Gout
  • Diabetes.

This medicine could cause harm to the heart of a newborn baby and could also cause a decrease in birth weight or cause negative adverse effects. Consult your physician if you are expecting or planning to get pregnant while taking caffeine and aspirin.Aspirin and caffeine could get into breast milk and harm a nursing child. It is not recommended to breastfeed with this medication.

How to take Aspirin and caffeine?

Follow the directions on the label or as directed by your physician. Don't use in greater than smaller quantities or for longer than is recommended.Take it with food if caffeine and aspirin can cause stomach upsets.Dissolve the powder or tablet in at least 4 ounces of water. Mix it up and drink it immediately.If you require surgery, be sure to inform your surgeon in advance that you're taking caffeine and aspirin. It is possible that you will need to discontinue using the medication for a short period of time.Don't take this medicine in the event that you notice an odor of vinegar that is strong in the aspirin or caffeine bottle. The medication may not be efficient.Place it in a cool, dry place far from heat and moisture.

What happens if I miss the dose?

Aspirin and caffeine are taken when required, and you might not be on a prescribed dosage schedule. If you're following a routine, take the dose you missed as soon as you remember. Avoid any missed doses if you are close to the time of the next dose scheduled. Do not attempt to replace any missed doses by taking extra medicine.

What happens if I overdose?

Get medical attention in an emergency or contact the poison help line at 1-800-222-1222.

What should be avoided?

If you're taking caffeine and aspirin to help prevent the risk of a heart attack or stroke, do not take Ibuprofen (Advil, Motrin). Ibuprofen could make aspirin or caffeine less efficient. If you have to use both of these medications, you should take Ibuprofen at least 8 hours prior to or 30 minutes after taking the caffeine and aspirin (non-enteric coated version).Do not drink alcohol if you take aspirin or caffeine. Drinking alcohol can increase the risk of bleeding in your stomach.Talk to your doctor or pharmacist prior to using or taking any prescription cold or allergy medication, such as diet pills or pain medications. The majority of medicines sold on the market include caffeine or aspirin. Combining certain medications can result in excessive amounts of this kind of drug. Examine the label to find out the presence of aspirin, ibuprofen, ketoprofen, naproxen, or caffeine.Consult your physician before taking caffeine or aspirin when you are taking an antidepressant like escitalopram, citalopram, or fluoxetine (Prozac), fluvoxamine, sertraline, paroxetine (Zoloft), trazodone, or vilazodone. The combination of any of these drugs with an NSAID could cause bleeding or bruises easily.

Interaction with other drug

Other drugs can interfere with caffeine and aspirin in the form of prescription or over-the-counter drugs, vitamins, and herbal products. Inform your health professionals about the medicines you are taking currently and all medicines that you decide to stop or change your use of.