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Generic name: laureth-9 (polidocanol) (LAWR-eth-9)
Brand names:
such as Asclera and Varithena
Drug class: clerosing agents

What is Asclera?

Asclera is a sclerosing drug. It is a sclerosing agent that increases the production of blood clots as well as scar tissue in certain kinds of veins. This can help reduce dilation of the veins with enlarged vessels.Asclera is a treatment for tiny, uncomplicated spider veins and varicose veins that are found in the legs. Asclera cannot treat varicose veins greater than 3 millimetres (about one eighth of an inch) in diameter.Asclera isn't a cure for varicose veins, and the effects of this medicine might not last for long.Asclera can also be employed for other purposes that are not covered in this guideline.


It is not recommended to take Asclera when you are allergic to laureth-9 and polidocanol. You should also not take it in the case of disorders of blood clots, like deep vein thrombosis (DVT), which is the swelling of the vein caused by a blood clot, as well as Buerger's disorder.Before receiving Asclera, inform your doctor about any allergies or medical conditions.Contact your doctor. If you experience any pain, burning, or even swelling near the IV needle after Asclera is administered, You will be closely monitored following your injection to ensure that the medication does not cause negative consequences.Follow your doctor's advice regarding how to take care of yourself after receiving Asclera.For 2 to 3 days following treatment with Asclera, avoid exposure to sun or tanning beds, saunas, or hot tubs. Don't apply the heating pad or ice to the affected leg without the advice of your doctor. Avoid vigorous or strenuous exercises or sitting for prolonged durations of time, for example, long-distance travel in a vehicle or on a plane.

Before you take this drug

You shouldn't take Asclera. If you are allergic to laureth-9, lauromacrogol 400, or the chemical polidocanol, Also, we are suffering from:

  • A blood clot disorder, like deep vein thrombosis (DVT) (also known as thrombophlebitis) (swelling in a vein triggered by an encasement of blood),
  • Buerger's syndrome (a condition that causes blood clots that affect the legs and arms)

To ensure that you are able to comfortably receive Asclera, consult your physician about all medical issues or allergies.FDA pregnant category C. It isn't clear whether Asclera can harm an unborn baby. Consult your physician if you are expecting or planning to become pregnant while taking Asclera. It isn't known if laureth-9 gets into breast milk or if it is harmful to nursing babies. It is not recommended to breastfeed while you're using Asclera.

Similar/related drugs

polidocanol, varithena, sotradecol, and sodium tetradecyl sulphate

How to take Asclera?

Asclera is injected using tiny needles right into a varicose vein, or spider vein. The injection will be administered in a hospital or clinic location.The number of treatments you will receive will be contingent on the number of varicose veins or spiders being treated.Asclera is administered gradually into your vein. Your medical professionals will apply some force to the vein throughout the injection.Inform your healthcare provider whether you feel any pain, burning, or swelling near the IV needle after Asclera is administered. You will be closely monitored following your injection to ensure the medication isn't causing negative side effects.Once the needle has been taken out of the vein, an elastic bandage or stocking is applied to the leg to stop blood clots from forming.After your treatment session has been completed, your medical team may ask you to take a walk for 15 to 20 minutes. Your doctor might instruct you to walk every day for a couple of days following the treatments with the asclera.It's possible to require compression stockings for a few days or even weeks after receiving your treatment using Asclera. Follow your doctor's advice on how to care for yourself after receiving this medication.It is possible that you will require additional sessions of treatment with Asclera to get the best treatment for your varicose vein. A minimum of one week should be allowed between treatment sessions.

What happens if I miss the dose?

Because you'll be receiving Asclera in a hospital setting, you're not likely to skip the dose.

What happens if I overdose?

Get medical attention in an emergency or contact the Poison Help Line toll-free at 1-800-222-1222.Intoxication can trigger severe skin reactions like burning, discoloration, or injury where the injection was administered.

What should be avoided?

Avoid strenuous or intense exercise for a period of 2 to 3 days following your treatment. Avoid sitting for prolonged periods of time, like travelling long distances in a car or on a plane.Avoid exposure to the sun and tanning beds, as well as saunas or hot tubs, for the duration of two or three days after treatment. Don't apply the heating pad or ice to the affected leg without consulting your physician.

Side effects of Asclera

Contact a medical professional immediately. If you experience any of the following signs that indicate an allergic reaction: hives; running nose; sneezing; difficulty breathing; swelling of your lips, face, or tongue,

Contact your healthcare providers immediately in the event of an adverse reaction that is serious, for example:

  • Extreme pain, burning, or any other abrasion on your leg.
  • Skin discoloration or changes after an injection was administered
  • Sudden, severe migraine, confusion issues with speech, vision, or balance
  • Discomfort, swelling, or redness in either or both legs;
  • Extreme numbness, which does not disappear;
  • Trouble breathing, heartbeats that beat, pounding, or a fluttering chest trouble breathing, pounding heartbeats, or fluttering in your chest
  • Confusion, feeling like you might pass out.

The most common asclera-related side effects could be:

  • Slight numbness or tingling
  • Mild headache, dizziness;
  • An increase in volume of hair on the treated leg; increased hair growth on the treated leg;
  • Mild pain or warmth minor itching, and minor bruising after an injection was administered.

This list does not represent all possible side effects associated with taking this medication.Other side effects could occur. Consult your physician for advice regarding medical adverse effects. Report any adverse reactions directly to the Food and Drug Administration by calling their hotline, 1-800-FDA-1088.

Interaction with other drug

It is unlikely that other medications you consume or inject will affect the asclera that is used for treating varicose veins. However, many medications may interact with each other. Tell your doctor about all the medicines you use.These include prescription, over-the-counter vitamins and herbal products.Don't begin an entirely new drug without consulting your physician.