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What is Anidulafungin?
Anidulafungin is an antifungal medication that treats candida (yeast) infections that occur in the stomach or in the blood in children and adults who are at least 1 month old.Anidulafungin also helps treat esophageal candida infections in adults.Anidulafungin can also be employed for other purposes that are not covered in this medication guide.
Side effects of Anidulafungin
See a doctor immediately. If you are experiencing symptoms or warning signs of an allergic response, like hives, trouble breathing, or swelling of your lips, face, or tongue,Certain side effects can occur after the injection. Inform your doctor immediately. If you experience lightheadedness, if you feel warm, itchy, sweaty, or tingly, or if you experience chest tightness or difficulty breathing,
Anidulafungin may cause serious side effects. Consult your doctor immediately in the event that you experience:
- Feeling lightheaded, like you're passing out;
- Trouble breathing
- Very little or no urine, black urine, pain or burning sensation when you urinate
- Abdominal pain and bloating
- Simple bleeding, unusual bruising, red or purple spots on the skin
- Low potassium: leg cramps, constipation, irregular heartbeats, fluttering of your chest, thirst, or urination. You may also experience numbness, tenderness in muscles, or a feeling of limpness.
- Low red blood cells (anemia)--pale skin sensation of fatigue, unusually tired, feeling lightheaded or short of breath, cold hands and feet; the
- (in babies) symptoms that include extreme fatigue, fussiness, feeding issues or vomiting.
Common adverse effects of anidulafungin could include:
- Tests for abnormally high liver function;
- Low blood sugar (hunger, sweating, irritability, dizziness, feeling shaky);
- White patches or sores in your throat or mouth;
- Low blood pressure and feeling lightheaded
- Bleeding or anaemia in the nose
- Fever;
- Stomach pain, indigestion, nausea, vomiting, diarrhoea;
- Low potassium
- Headache or difficulty sleeping
- Rash.
This list may not contain all possible side effects associated with using Teva pharmaceutical products.. Other side effects could occur. Contact your doctor to seek medical advice on adverse effects. Please call 1-800-FDA-1088 immediately if any adverse reactions arise from using any product from FDA-regulated stores.
Warnings
Follow the directions on the label of your medication and on the label of your package. Inform your healthcare professionals about your medical issues, allergies, and the medicines you are taking.
Before you take this drug
It is not recommended to use anidulafungin If:
- You are intolerant of anidulafungin or similar medicines like caspofungin, micafungin, or
- You are a victim of hereditary fructose intolerance the condition that causes you to be unable to process fructose-containing sugars (such as those found in certain juices or fruits).
Inform your doctor if have ever suffered from the liver condition.Inform your doctor immediately if you are breastfeeding or pregnant.
How to take Anidulafungin?
Follow all instructions on the prescription label and go through all medication guides or instructions. Make sure you use the medication exactly as prescribed.Anidulafungin is administered by injection into a vein. The healthcare professional will provide your first dose and instruct you on how to make use of the drug on your own.Anidulafungin should be mixed with liquid (diluent) and then diluted in an IV bag prior to taking it. Take note of and adhere to any instructions for use that are included in your medication. Talk to your pharmacist or doctor for clarification if you aren't sure about the instructions.Make an injection only when you are able to give it. Avoid using it when the medication has changed colour or contains particles. Contact your pharmacist to inquire about a new medication.The medicine should be administered slowly, and the infusion may last anywhere from 45 minutes to 3 hours for completion.It's possible that you'll need an infusion pump syringe to administer anidulafungin to children. Follow your doctor's directions closely.Anidulafungin may be administered for up to 7 days after the symptoms have gone away or for as long as 14 days after laboratory tests confirm that the disease is gone. Make sure to take this medicine for the prescribed duration. Anidulafungin is not a treatment for the symptoms of a viral disease like influenza or the commonly occurring cold.It is possible that you will require frequent blood tests to monitor the liver's function.Refrigerate empty bottles in the refrigerator. Avoid freezing.Once you've mixed your diluent in the vial and stored the vial at room temperature for up to 24 hours prior to the time you dilute the mix in an IV bag and administer the injection,The mix solution that is left in the IV bag can be stored at room temperature for a period of at least 48 hours. Do not freeze.Every bottle is intended for one-time use only. Dispose of it after one use, regardless of whether there's still some medicine within.After treatment with anidulafungin, you might be prescribed another antifungal medicine to stop your candida esophageal infection from returning. Continue to take this medication for as long as your physician prescribes.Don't use anidulafungin in a disdiluted solution if it's changed colour or has particles. Contact your pharmacist to inquire about the latest medications.Make use of a needle and syringe just once, and then put them in a puncture-proof "sharps" container. Make sure you follow local or state laws regarding how to dispose of the container. Make sure it is out of reach of pets and children.
Details on dosage
Usual Adult Dose for Candida:
Initial dosing regimen: 200 mg IV in one single loading dose on Day One.Dosage for maintenance: 100 mg IV, at least once per day thereafter.
Comments:
The duration of treatment should be determined by your patient's response to treatment.
In general, antifungal treatment is recommended for at most 14 days following the last positive test.
Use: To treat candidemia and the following Candida infections: abscess intraabdominal or peritonitis
Usual Adult Dose for Esophageal Candidiasis:
Initial dosing dose: 100 mg IV as an initial loading dose on Day 1.Dosage for maintenance: 50 mg at least once per day thereafter.
Therapy duration: at least 14 days, or at most 7 days, following the resolution of symptoms.
Comments:
The duration of treatment should be based on the patient's medical response.
In light of the possibility of relapse for HIV-infected people The use of suppressive antifungal therapies could be considered following the therapy regimen.
Use: In the treatment of candidiasis esophageal.
Usual Paediatric Dose for Candida:
1 month or more:
Initial loading dose of 3 mg/kg should be administered intravenously on Day 1.Maximum dose: 200 mg/dose
Maintenance dose: 1.5 mg/kg IV once each day for the next 7 days.
Maximum dose: 100 mg/dose
Comments:
Overall, antifungal treatment should be continued for at least 14 days following the first positive test.
Use: To treat candidemia as well as the following Candida infections: abdominal abscess and peritonitis
What happens if I miss the dose?
Consult your physician for instructions in case you missed a dose.
What happens if I overdose?
For medical emergencies, seek emergency medical attention or contact the Poison Help Line toll-free at 1-800-222-1222.
What should be avoided?
Follow your doctor's advice regarding the food or beverage.
Interaction with other drugs
Other medications may also influence anidulafungin, such as prescription and non-prescription medicines, vitamins, and herbal remedies. Discuss with your doctor your current medications as well as any medications you are about to start or stop taking.