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Generical name: antivenin (Crotalidae) polyvalent (AN Tye VEN (kroe TAL I DEE) POLE EE VAY LENT)
Brand names: Anavip (equine) Anavip CroFab
Class of drugs: antitoxins and antivenins

What is Anavip?

Crotalidae antivenin is a venom-fighting substance that can be used to treat someone who was bitten by poisonous snakes such as a rattlesnake or a water moccasin.Anavip could also be used to treat conditions that are not covered in this guideline for medication.

Side effects of Anavip

Take immediate medical care. If you are experiencing symptoms that indicate an allergy, such as itching, hives, or redness, wheezing, breathing difficulties, or feeling lightheaded, or swelling of your lips, face, tongue, or throat,Certain side effects can occur after the injection. Contact your physician immediately when you experience a fever, feel sick, or suffer from lower back discomfort or breathing difficulties.

Anavip could result in severe adverse reactions. Consult your physician immediately. If you suffer from:

  • Simple bleeding, unusual bruising (nosebleeds, bleeding gums, bleeding nose, blood resulting from injuries);
  • Red or purple pinpoints under your skin
  • Excessive menstrual bleeding
  • Itching, rash, or skin redness a few days after treatment with crotalidae antivenin.

Common adverse effects of anavip could include:

  • Itching;
  • Rash;
  • Nausea;
  • Back discomfort.

This list may not provide all possible side effects of chemotherapy treatment.Other side effects could occur. Contact your doctor to seek medical advice on adverse effects. Report any adverse reactions directly to the FDA at 1-800-FDA-1088.


If you are able to, before taking Anavip, inform your physician whether you're allergic to any food or animals, as well as other allergens.In an emergency, it might not be feasible until you receive treatment to inform your medical professionals about your medical conditions or if you're breastfeeding or pregnant. Be sure that any doctor who cares for you in the future knows you've received this medication.

Before you take this drug

If it is possible prior to receiving Crotalidae antivenin, you should inform your physician if you are allergic to any animal, food, or other substances. Before administering this medicine, your medical professional must know if you're sensitive to papaya or papain, horses, sheep, pineapples, dust mites, or latex

Inform your doctor if you suffer from:

  • A bleeding or blood clotting disorder, for example, haemophilia;
  • Cancer;
  • Congestive heart failure;
  • An overactive thyroid.

Crotalidae antivenin is produced from the plasma or blood of healthy sheep or horses. Plasma or blood from animals may contain viruses or other infective agents. Blood and plasma are analysed and treated to lower the chance of them carrying infectious agents; however, there is a slight possibility that they may transmit the disease. Consult your doctor about the potential risks and benefits of this treatment.There is currently no consensus as to how this medication will impact on a newborn baby. Consult your physician if you are expecting.It is unclear if Crotalidae antivenin gets into breast milk or if it can harm the nursing infant. Consult your physician if you are breastfeeding a child.In a situation of emergency, it might not be possible to notify your carers that you are breastfeeding or pregnant. Be sure that any doctor who cares for your baby or your pregnant mother has been informed that you've taken this medication.

How to take Anavip?

Treating with Crotalidae antivenin should begin at the earliest opportunity when you first notice signs of a bite from a snake (fang marks on the skin, swelling or redness, and poor vision; sweating; an increase in the amount of saliva; vomiting; blood loss that is not controlled; difficulty breathing; weakness and loss of the muscle's control; or weakness of the body or face).Crotalidae antivenin injections are made into veins via an IV. Healthcare professionals will administer this injection. Crotalidae antivenin should be administered slowly. The IV infusion may last for at least 60 minutes.Anavip is most effective when given within 6 hours of the bite occurring.You will be closely monitored for at least 60 minutes following receiving Crotalidae antivenin in order to ensure that this medication will help your condition.You might need more doses if your health does not improve after the initial dose. After your symptoms have been brought under control, you could receive more doses every 6 hours, for as long as 18 hours, or even longer. Your physician will decide the duration of treatment with Crotalidae antivenin.A snake venom bite could increase the chance of bleeding. This can be serious or life-threatening. Contact your doctor or seek medical emergency attention when you experience bleeding that doesn't stop.Your doctor should examine your progress for two weeks or more after you have been treated with antivenin from Crotalidae. You might require re-treatment with this medication or other medications that may help your blood form clots.

What happens if I miss the dose?

Since you'll be receiving Crotalidae, an antivenin, in a medical setting, you're not likely to be able to miss the dose.

What happens if I overdose?

Because Anavip is administered by a doctor in a medical environment, it is not likely for an overdose to occur.

What should be avoided?

After getting bitten by a snake You should stay clear of actions that could increase your chance of sustaining injury or bleeding. Make sure to take extra precautions to avoid bleeding when cutting or brushing your teeth.

Interaction with other drugs

Other medications can be incompatible when used in conjunction with an antivenin (Crotalidae) multivalent, such as medications that are available over the counter and prescription, vitamins, and herbal products. Inform your healthcare providers about all medications you are currently taking and any medication you begin or stop taking.