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Name of The Generic: Aducanumab [A-due-KANue-mab] A-due-KAN-ue-mab [ ADUE –
Name of The Brand: Aduhelm
Dosage Format: Intravenous solution (AVWA 100 mg/mL)
Drug Class: Miscellaneous central nervous system agents

What is Aducanumab?

Aducanumab is a drug used to treat patients suffering from Alzheimer's disease.Aducanumab could also be used to treat conditions that are not mentioned in this guideline.

Side Effects Of Aducanumab

See a doctor immediately. If you are experiencing symptoms that indicate an allergic reaction, such as hives, difficulty breathing, or swelling of your lips, face, or tongue,

There are some side effects that can happen when you inject. Inform your physician that you are feeling dizzy, nauseated, lightheaded, or sweaty. or experience headaches, chest tightness, back

discomfort, breathing difficulties, or a swelling on your face.

Aducanumab may cause the brain to bleed or swell temporarily. the brain. Contact your doctor in the event of:

  • Dizziness, confusion;

  • Problems walking;

  • Seizures;

  • Nausea;

  • Vision changes.

Common adverse effects of the drug include:

  • ARIA with symptoms or with signs that show to be present on MRI;

  • Headaches migraine

  • Falls.

It's not a comprehensive list of the possible reactions, as other consequences could also occur.

Consult your physician for advice on the effects of medicine.

If you have any concerns, report the reaction to the FDA by calling 1-800-FDA-1088.


Aducanumab may cause some temporary swelling or bleeding within the brain. Usually, it can be cured with time. The condition may not cause any symptoms, but it could be severe. Contact your physician. If you experience nausea, headaches, dizziness, confusion, or changes in your vision,

Before You Take This Drug

Aducanumab could cause a condition known as Amyloid-Related Imaging Abnormalities, or "ARIA."ARIA is an intermittent swelling or small areas of bleeding within the brain that generally disappears with time. The doctor could do the MRI on your head prior to and during treatment with the drug aducanumab. Talk to your doctor about the risk.

It is unclear whether aducanumab can harm a baby who is not yet born. Consult your physician if you are expecting or planning to become pregnant.Consult a physician to determine whether it is safe to breastfeed during treatment with aducanumab.

How to Take Aducanumab?

Aducanumab is administered into a vein by a healthcare professional.The medicine is administered slowly over the course of an hour.

Aducanumab is typically given at least every four weeks with at least 21-day intervals between treatments.It is necessary to have brain MRIs during treatment with aducanumab.

Details on Dosage

Usual Adult Dose for Alzheimer's Disease:

It is necessary to do a titration prior to treatment beginning. Doses are infused for one hour every four weeks.

Infusions 1 and 2: 1 mg/kg IV

Infusions 3 and 4: 3 mg/kg IV

Infusions 5 and 6: 6 mg/kg IV

Maintenance dose: 10 mg/kg IV once every 4 weeks


Administration via IV infusions roughly every 4 weeks and at minimum 21-day intervals.

Patients who participated in clinical trials showed moderate cognitive impairment or a mild Alzheimer's stage, and there was no evidence of risks or

Effectiveness data for initiating treatment at later or earlier phases of the illness were examined.

This drug was approved under expedited approval based on a reduction in amyloid beta plaques that was observed in patients who were treated in clinical studies. The approval of this drug may be contingent on the confirmation of clinical efficacy in confirmatory studies.

Use: To treat symptoms of Alzheimer's disease in patients suffering from slight cognitive decline or mild dementia.

What Happens If I Miss a Dose?

Contact your doctor for advice in the event that you don't make an appointment for your augmentanumab injection.

What Happens If I Overdose?

In a medical facility, an overdose could be taken care of quickly.

What Should Be Avoided?

Follow the instructions of your physician regarding any restrictions on your food, drink, or activity.

Interaction With Other Drugs

Discuss with your doctor any other medications you take, particularly those to stop or treat blood clots, such as aspirin.

Other medications may interact with the effectiveness of aducanumab. These include prescription and non-prescription medicines, vitamins, and herbal products. Inform your physician about any other medications you take.




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