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Acthrel (Intravenous)

Generic name: corticorelin ovine triflate [kor-ti-koe-rel-in-oh-vine-trye-floo-tate]
Drug class: corticotropin

What is Acthrel?

Corticorelin injectables of ovine triflate are employed as the test for identifying Cushing syndrome.

This medication should be administered under the guidance of a doctor.


Your physician will be able to monitor the progress of your treatment closely when you take this medication. Your doctor will be able to determine if the medication is functioning properly and whether you are able to continue receiving it. Tests for blood may be required to determine if there are any unwanted side effects.

The possibility of allergic reactions can arise while taking this medication. Contact your physician right away if you experience an outbreak of itching or rashes on your skin or redness or flushing of your neck, face, or upper chest. Massive, hive-like swellings of the eyelids, face and lips, tongue, throat, hands, feet, sex organs, or breathing difficulties.

Don't take any other medications without discussing them with your physician. These include prescription and nonprescription (over-the-counter) medications as well as herbal or vitamin supplements.

Before you take Acthrel

When deciding whether to conduct an examination for diagnosis, the potential risks associated with the test should be evaluated against the benefits it can bring. It is a choice that you and your physician will make. Other factors could influence the results of the tests. To pass this test, these factors must be considered: 


Inform your physician if you are ever experiencing any strange or allergic reactions to this medication or any other medication. Inform your healthcare specialist if you suffer from any other allergies, like food, dyes, preservatives, or even animals. When using products that are not prescription-only, you must review the label and package ingredients attentively.


The studies that have been conducted up to now have not revealed specific problems for children that could limit the effectiveness of acthrel (r).


There is no information available about the connection between age and the adverse effects of acthrel (r) in patients with geriatric diseases.


There is no research on women that can determine the risk to infants when taking the medication while nursing. Consider the possible benefits versus the risks that could be associated with using this medication during breastfeeding.

How to take Acthrel?

An experienced nurse or healthcare professional can give you the medicine at a hospital. The medicine is administered through an injection into the vein in which you are located.

Side effects of Acthrel

In addition to their beneficial benefits, some medicines may have unwanted consequences. Though not all adverse effects can happen, if they do, they might require medical attention.

Talk to your physician or nurse as soon as possible when one of the following adverse effects happens:

Mild effects

  • Breathing difficulty or labored

  • The feeling of warmth

  • Itching, hives, or itchy skin

  • Large, hive-like swellings in the eyelids, face, and lips. It can also be seen on the tongue, throat, hands, feet, legs, or even sex organs.

  • Redness on the skin

  • Redness in the face and neck as well as, occasionally, the upper chest

  • The chest is tight.

Contact emergency aid immediately. If any of the following symptoms of an overdose appear:

Adverse side effects

  • Difficult or labored breathing

  • Extreme redness in the facial area

Additional side effects that are not mentioned can also happen in certain patients. If you notice any other symptoms, consult your doctor.

Interaction with other drugs

While certain medications should not be combined in any way, in other instances, two medications can be combined even though there is a chance of interaction. If this happens, the doctor might want to adjust the dosage or take other precautions. Discuss with your doctor or healthcare provider whether you're taking a prescription medication or a non-prescription (over-the-counter [otc]) medication.

Involvement with alcohol, tobacco, and food

Certain medications should not be taken at or near the time you eat food or eat certain kinds of food, as interactions could happen. The use of tobacco or alcohol along with some medicines could create interactions. Talk to your doctor about when you take your medication if you are taking it with alcohol, food, or tobacco.