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Generic name: Haemophilus b conjugate (prp-t) vaccine [hem-off-il-us-b-kon-ju-gate] brand names: acthib, hiberix
Drug class: bacterial vaccines

What is ActHib?

Haemophilus influenza, type b (Hib), is a type of bacteria that can trigger serious illnesses such as breathing difficulties as well as meningitis. Hib illness typically affects children and could be fatal.

Acthib can be used to stop the spread of this illness in children and can be used in conjunction with vaccinations to guard against other maladies.

Acthib is administered to kids between the ages of 2 months and 5 years old. Hiberix will be provided to children aged between 6 weeks and four years old (prior to their fifth birthday).

The vaccine is administered by exposing your child to only a tiny amount of bacteria or the protein produced by the bacterium, which triggers your body to build up immunity to the infection. This vaccination will not cure an infection that is active and has already begun to manifest in your body. Moreover, it does not shield against other forms of influenza.

As with all vaccines, the Hemophilus-b conjugate vaccine will not offer protection against illness to everyone.


Discuss with your physician whether your child is taking other medications or suffers from other medical conditions or allergies.

Before you Take this Drug

It is not recommended for your child to receive the vaccine if they have previously had an allergic reaction to the Hemophilus b vaccine, tetanus vaccine, or meningococcal vaccine.

If your child suffers from one or more of these conditions, it may be necessary for this vaccination to be delayed or perhaps completely avoided.

  • Your immune system was severely suppressed as a result of a condition (such as cancer or hive) or from taking certain medications, such as chemotherapy, steroids, or radiation.

  • A history of seizures.

How to take vaccination?

This vaccine is injected into the muscle. The child is given the injection at a physician's office or in a clinic.

This vaccination is delivered as a series of shots. The first shot is typically given at two months old. The subsequent shots are offered at 4 and 6 months old. The booster shot can be given at 15–18 months old. The first shots can be administered as early as six weeks old.

The schedule for your child's boosters might differ from the guidelines below, particularly when the child doesn't start the series of shots until seven months old. Following the advice of your doctor and the recommendations of the health department in your state

Your physician may suggest the treatment of pain and fever with an aspirin-free pain reliever like acetaminophen (Tylenol) as well as ibuprofen (motrin, advil, and others) after the shot has been administered and over the next 24 days. Use the instructions on the label as well as your doctor's directions on what dosage of acthib you should give your child.

It is particularly important to prevent fevers from happening when a child suffers from seizures, such as epilepsy.

What happens if I miss a dose?

Consult your physician if you are likely to miss a dose booster or if you fall behind. Your next dose must be taken as quickly as possible. There's no reason to start again.

Make sure that your child is receiving the doses recommended by the vaccine. If your child is not able to get the complete series of vaccinations, he might not be 100% protected against this disease.

What happens if I overdose?

The risk of an overdose from this vaccine is unlikely to occur.

What should be avoided following the vaccination?

Check your doctor's recommendations regarding restrictions on foods, beverages, or activities.

Side effects of the Vaccine

Contact emergency medical assistance. If your child shows symptoms of an allergic reaction such as asthma, such as hives or swelling on the lips, face, and tongue,

Be aware of any adverse reactions your child experiences following the vaccination. After the child has received an additional dose, you must let the doctor know whether the shot before resulted in any adverse negative effects.

Mild effects

  • A seizure;

  • Cry for up to an hour as well as

  • Extremely high temperature (within just a couple of hours or days following the vaccination).

Adverse side effects

  • Fever;

  • Fussiness, irritability, crying;

  • drowsiness;

  • Loss of appetite or

  • Inflammation, pain, or redness at the site where the shot was administered.

This is not an exhaustive list of possible side effects, and other side effects could occur. Consult your physician to get medical advice regarding the effects of your vaccine. The best way to report negative side effects is to call health and human services at 1-800-822-7967. Us department of health and human services at 1-800-822-7967.

Interaction with other drugs 

Prior to receiving the vaccine, inform the vaccine service about other vaccines your child has had.

Additionally, inform the vaccine doctor if your child has been treated with drugs or other treatments that could affect the immune system. These include:

  • Steroid medicine;

  • Treatment for cancer;

  • Medication for treating the symptoms of psoriasis, rheumatoid arthritis, and other auto-immune disorders, as well as

  • Medications to prevent or treat organ donation rejection.

If your child is taking some of these medicines or is taking any of these medications, then he or she might not be able to get the vaccine or might have to wait until all other treatments have been completed.