What is Magnevist?
Magnevist is an agent for contrast that has magnetic properties. It is employed in conjunction with magnetic resonance imaging (MRI) to allow organs, blood vessels, and other non-bony tissue to be more easily seen in the MRI. Magnevist is used to diagnose specific disorders of the blood vessels, the brain, and the spin (central nervous system). Magnevist can also be used for reasons not mentioned in this guideline for medication.
Warnings
Magnevist could cause a life-threatening illness in patients who suffer from advanced kidney disease. The signs of this condition are:
- Itching, burning, swelling, scaling, and tightening or hardening your skin.
- Weakness in the muscles.
- Joint stiffness that affects your hands, arms, feet, legs, or hands.
- Painful bone pain that is deep in your ribs or in your hips.
- Problems getting it moving.
- Skin discoloration or redness.
Before you receive Magnevist, inform your doctor that you suffer from kidney disease or are taking dialysis. You may be unable to take this medication. Be sure to inform your doctor if you've recently taken any contrast medication that is similar to Magnevist.
Tell your doctor if you suffer from diabetes or high blood pressure, liver disease, or a heart rhythm disorder, as well as allergies or asthma in the event that you are older than 60 years old, if you've ever experienced an allergic response to any contrast substance, or if you recently suffered an injury, operation, or infection that was severe. Your physician or healthcare professional might want to observe your condition for a short period following the conclusion of your test. This is to ensure you do not suffer undesirable reactions or side effects.
Before you take this drug
Magnevist could cause a life-threatening illness in patients suffering from an advanced form of kidney disease. It is not recommended to take this medicine if you suffer from kidney disease or are taking dialysis. Gadopentetate dimeglumine could remain inside your body for a number of months or even years following the administration of this medication. It isn't known if it could trigger health issues in those who have kidneys that function properly. Inform your physician that you've had multiple scans using a contrast agent. Also, specify the date of the previous scan. It is not recommended to be treated with Magnevist if you have an allergy to gadopentetate dimeglumine.
To make sure that this medicine is suitable for you, inform your physician if you have any of the following:
- Kidney problems.
- Any kind of reaction to any contrast agent.
- Diabetes.
- High blood pressure.
- Liver disease.
- Asthma, hay fever, food and drug allergies.
- An injury, surgery, or severe infection.
- If you are older than the age of 60.
It isn't known if Magnevist can cause harm to a baby who is not yet born. Inform your doctor if you are expecting or planning to be pregnant. It isn't known if gadopentetate dimeglumine gets into breast milk or whether it affects the nursing infant. Consult your physician if you are breast-feeding.
Similar or related drugs
Gadavist, Dotarem, gadobutrol, gadoterate meglumine, gadoteridol, Clariscan, and gadodiamide
How to take Magnevist work?
Magnevist is given as an IV injection into a vein. The healthcare professional will offer the injection. Inform your doctor that you are experiencing the sensation of burning or discomfort as well as swelling after Magnevist is administered.
Your physician or health professional may decide to monitor your condition for a short period after the test has been completed. This is to ensure you don't have undesirable negative side effects or delayed reactions.
Details on dosage
Adult Typical Dose for CNS Magnetic Resonance Imaging:
0.1 millimol/kg (0.2 milliliters/kg) for a quick intravenous injection bolus at a dose that doesn't exceed 10 mL every 15 seconds. The dosing of patients who weigh more than 286 pounds hasn't been investigated. To ensure a complete and thorough administration of the medium, the injection must be followed by a flush of saline of 5 mL or less.
Adult Standard Dose for Vascular Magnetic Resonance Imaging:
0.1 millimol/kg (0.2 milliliters/kg) in a rapid bolus intravenous injection at a rate of not more than 10 mL in 15 seconds. The dosing of patients who weigh more than 286 pounds hasn't been researched. To ensure a complete and thorough administration of the medium, the injection must be followed by a saline flush of at least 5 mL.
Pediatric CNS Magnetic Resonance Imaging Dose:
Between 2 and 18 years old: 0.1 mmol/kg (0.2 mL/kg) in an intravenous bolus injection in a rapid fashion with a dose not exceeding 10 mL every 15 seconds. Dosing for patients with a weight in excess of 286 pounds hasn't been investigated. To ensure a complete and thorough administration of the medium, the injection must be followed by a saline flush of at least 5 mL.
Pediatric Vascular Magnetic Resonance Imaging Dose:
From 2 to 18 years old: 0.1 mmol/kg (0.2 mL/kg) in a rapid bolus intravenous injection, with an amount not exceeding 10 mL in 15 seconds. Dosing for patients with a weight in excess of 286 pounds hasn't been researched. To ensure a complete and thorough infusion of the medium, the injection must be followed with a saline flush of a minimum of 5 mL.
What happens if I miss a dose?
Because Magnevist is only administered for your MRI and not during your MRI, you won't be following a schedule of dosing.
What happens if I overdose?
Since the medicine is prescribed by a health expert in a medical environment, it is highly unlikely for an overdose to occur.
What should be avoided?
Follow the instructions of your physician regarding any restrictions on your food, drink, or activity.
Adverse effects of Magnevist
See a doctor immediately. Get medical attention immediately if you show symptoms that you are experiencing an allergic reaction, such as hives, breathing difficulties, and swelling of your lips, face, and tongue. Certain side effects associated with Magnevist can occur for several days following the injection.
Magnevist could cause a life-threatening illness in patients suffering from severe kidney problems. Contact your physician immediately if you experience any signs of this disease, like:
- Itching, burning, swelling, scaling, and hardening or tightening your skin.
- Muscles weak.
- Stiffness of joints in your hands, arms, legs, feet, or arms.
- Painful bone pain that is deep in your ribs or hips.
- Difficulty getting moving trouble moving.
- Skin discoloration or redness.
Make sure to contact your doctor at the earliest opportunity if you are suffering from:
- Kidney issues The result is a lack of or no urine; pain or difficulty urinating; swelling of the ankles or feet; being tired or exhausted.
- Swelling, bruises, bleeding, itching, burning, or changes to the skin in the area where the injection was administered.
Common Magnevist adverse effects could include:
- Headache, dizziness.
- Nausea.
- The sensation of coldness, warmth, or pain in the area where the medication was injected.
This is not a comprehensive list of possible side effects, and other side effects could occur. Consult your physician for advice regarding medical adverse effects. You can report any adverse reactions to the FDA at 1-800-FDA-1088.
Interaction with other drugs
Other medications may be incompatible with gadopentetate dimeglumine, which includes prescription and over-the-counter medicines, vitamins, and herbal products. Inform your physician about the medicines you are currently taking as well as any medications you are about to start or stop taking.
