What is Synarel?
Synarel is used for the treatment of central early puberty in both girls and boys. Central precocious puberty is an early sexual development in girls and boys that begins before the age of 8 or 9. The child will also have bone development that is above their age.
Synarel can also be used to treat endometriosis among women over 18 years of age. This medication guide does not list all possible uses of Synarel.
Side effects of Synarel
If you experience any of the following symptoms of an allergic reaction, seek immediate medical attention: hives, chest pains, difficulty breathing, swelling of your lips, face, tongue, or throat.
Synarel may cause serious side effects. If you experience:
- Vaginal bleeding or vaginal spotting
- Pelvic pain or swelling
- A seizure;
- Depression: mood changes, low self-worth feelings, lack of interest in activities you used to enjoy, sleep problems, and thoughts of harming yourself.
- Increased pressure in the skull can cause severe headaches, ringing ears, dizziness, and nausea, as well as vision problems or pain behind the eyes.
- Signs of a pituitary problem: sudden headache; confusion; vision changes; vomiting.
Some children who used Nafarelin developed new mental disorders or had existing problems worsen. If your child shows any abnormal changes in behavior or mood (such as anger, aggression, crying, or feeling restless), call your doctor immediately.
Synarel can cause some side effects during the first month. However, this is not a reason for stopping the medication. Inform your doctor of any side effects that are bothersome or persistent.
Synarel side effects may include:
- Vaginal bleeding, discharge, or dryness;
- Hot Flashes
- Acne;
- Breast size can increase or decrease.
- Runny nose
- Headaches, muscle pain;
- Mood changes
- Reduced interest in sex
- Itchy, flaky, or red rash
- Increased body odor
- Increased pubic hair growth
There may be other side effects. For medical advice on side effects, call your doctor. The FDA can be contacted at 1-800-FDA-1088 to report side effects.
Warnings
Do not use this product if you are pregnant. Some children who use nafarelin develop new mental disorders or have existing ones worsen. If your child shows any abnormal changes in behavior or mood (anger or aggression, crying or feeling restless), call your doctor immediately.
Nafarelin can also cause seizures. This is especially true for people who have experienced a seizure or have epilepsy. You may be at a higher risk of having a seizure if you are taking certain antidepressants. Synarel should not be used if abnormal vaginal bleeding has been detected without a medical checkup.
Before you take this drug
Synarel should not be used if you have an allergy to nafarelin or other similar medications such as goserelin, leuprolide, histrelin, or triptorelin.
Women should avoid using Synarel.
- Undiagnosed abnormal vaginal bleeding;
- If you are breastfeeding or pregnant,
Tell your doctor about any of the following:
- Epilepsy or another seizure disorder
- Mental illness;
- A brain tumor or blood vessel issue;
- Polycystic ovarian disease
- Low bone mineral density;
- Osteoporosis
- If you are a heavy drinker or smoker,
Avoid using Synarel while pregnant. This drug could harm your unborn child. This treatment may require a negative pregnancy check. Despite the fact that this medicine can cause you to not ovulate or to have regular periods, you should still use an effective non hormonal contraceptive to prevent pregnancy when you are taking this medicine.
Synarel can reduce the effectiveness of hormonal birth control, such as birth control pills and skin patches. Barrier birth control can be used to prevent pregnancy. These include a condom, diaphragm, or cervical cap. Synarel should not be used while breastfeeding.
How to take Synarel?
Your doctor will test the medicine to ensure that it is right for your child. Read all the instructions or guides that come with your medication and follow the directions. Sometimes, your doctor will change the dose. You must take the medication exactly as it is prescribed. This medicine should not be missed. If you skip doses or do not use Synarel properly, it may lead to a hormonal imbalance and unwanted side effects.
Please read and follow the instructions for the use of nasal spray. If you don't understand the instructions, ask your pharmacist or doctor. When using nasal spray, tilt your head back slightly. Only use the prescribed number of sprays and wait at least 30 seconds in between each spray.
Your doctor should monitor your child's progress by conducting frequent medical tests. This is especially important during the first six to eight weeks of Synarel use. Nafarelin may increase hormones at the beginning of treatment. It may make your child's precocious symptoms worse for a brief time. If pubertal symptoms persist for more than a month, call your doctor. Synarel should not cause regular periods to continue. If your period continues for more than one month after starting this medication, tell your doctor.
Use a Synarel spray bottle for no more than 30 days. After 30 days, the medicine in the bottle will not be sufficient to give another full dose. Do not run out of medication by getting your prescription renewed before 30 days. Synarel should be stored upright at room temperature, away from moisture, heat, and light. Avoid freezing. When not in use, keep the bottle tightly closed.
What happens if I miss the dose?
If you are almost due for your next dose, skip the missed dose. Never take two doses of the same medicine at once. Synarel is highly important.
What happens if I overdose?
Call 1-800-222-1222 for poison help or seek immediate medical attention.
What should be avoided?
After using the spray, avoid sneezing or blowing your nose. Nafarelin can be less effective if you sneeze or blow your nose right after using the spray. Do not use any other nasal sprays for at least 2 hours following your dose of Nafarelin Nasal. Ask your doctor if you have a stuffy or runny nose before using nasal decongestant sprays.
Interaction with other drug
Tell your doctor what other medications you are taking, including:
- Antidepressants are a type of medication.
- Seizure medicine;
- Steroid medicine.
This list is incomplete. Synarel may be affected by other drugs, such as prescription and over-the-counter medicines, vitamins, and herbal products. This list does not include all possible drug-drug interactions.
