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Zortress

Name of the generic: Everolimus (Zortress) [ E-ver-OH-li-mus [ E-ver-OH-li-mus
Drug classes: MTOR inhibitors, selective immunosuppressants

What is Zortress?

Zortress decreases the immune system. The immune system assists to fight infections.The immune system also has the ability to combat and "reject" a transplanted organ, such as a liver or kidney. The reason for this is that the immune system perceives the transplanted organ as an intruder.

It is the Zortress version of everolimus and is used to stop organ rejection following a kidney or liver transplant. Zortress can be used in conjunction with cyclosporine and steroids, as well as other medicines.Invitor is another name for everolimus, which is used to treat specific forms of cancer. This guide to medication provides details only on Zortress.

Warnings

Zortress can increase the risk of getting ill or developing certain types of cancer by altering the way your immune system functions.

Infections that are fatal and often deadly can occur when you are treated with everolimus. Consult your doctor immediately if you notice symptoms of infection like chills or fever.

Zortress can trigger a blood clot to form in the vessels of your newly transplanted organ. Contact your physician immediately in the event of nausea or vomiting that causes fever, the presence of blood or urine in your system, dark urine, no or little urinary frequency, or discomfort on your stomach, in the groin area, low back, or on your side.

Before you take this drug

It is not recommended to take Zortress if you have an allergy to sirolimus and/or everolimus. Sirolimus.The use of Zortress increases the risk of getting serious infections or developing certain cancers, including lymphoma and skin cancer. Consult your physician about the risk you are taking in your particular situation.

Inform your doctor if you have ever suffered from:

  • Problems digesting lactose or galactose (sugar);
  • High cholesterol or triglycerides
  • The liver condition;
  • A heart transplant
  • Skin cancers in you or a family member.

Zortress could cause harm to an unborn baby. Use effective birth control during the time you take this medication and for a minimum of 8 weeks following your last dose. Inform your doctor when you are pregnant.

This medication can impact fertility (the ability to bear children) for both men and women. But it is essential for women to take birth control, as everolimus could cause harm to the baby if pregnancy occurs.

It isn't known if everolimus can be found in the milk of a nursing baby or whether it poses a risk to nursing babies. It is not recommended to breastfeed when you take Zortress.

How to take Zortress?

Zortress is typically taken twice a day (every 24 hours). Follow all the instructions on the prescription label, and make sure you read all medication guidelines or instructions sheets. Your doctor might alter the dose you take. Make sure you take the medicine precisely as prescribed.

Use this medicine at intervals that are evenly spaced by drinking a glass (8 ounces) of fluid.Use the medication either with or without food, but in the same manner each time. If you are also taking cyclosporine and tacrolimus, be sure to take both simultaneously.

Don't chew or crush a Zortress tablet. Take the tablet in whole.You'll require regular medical tests.Do not alter dosages or discontinue taking any medication without consulting your doctor.Maintain at room temperature, free of heat, moisture, and light.

What happens if I miss a dose?

Take the medication as quickly as you are able, but do not miss any doses if you are nearing the time to take the next dose. Don't take two doses at once.

What happens if I overdose?

Get medical attention in an emergency or contact the Poison Help line toll-free at 1-800-222-1222.

Avoid this

Do not get a "live" vaccine while using Zortress. The vaccine could not perform as well and could not completely protect you from diseases. Live vaccines comprise measles, mumps, measles, rubella (MMR), polio, and typhoid. Yellow fever, varicella (chickenpox), herpes zoster (shingles), and the nasal influenza (influenza) vaccine

Everolimus is a drug that can be absorbed into body fluids (urine, feces, or vomiting). Caregiver's should wear gloves made of rubber to clean up the person's bodily fluids, toxic trash, laundry, or change diapers. Clean hands prior to and after taking off gloves. Cleanse linens and clothing that have been soiled apart from the rest of the laundry.

Everolimus can increase the chances of developing skin cancer. Do not expose yourself to sunlight and tanning bed. Be sure to wear protective attire and apply sunblock (SPF 30 or greater) while you're outdoors.Grapefruit could interact with everolimus and lead to undesirable negative side effects. Beware of the consumption of grapefruit or grapefruit juice when taking Zortress.

Side effects of Zortress

Seek medical attention immediately. If you are experiencing symptoms of an allergy reaction, Zortress: hives, itching, discomfort in the skin, difficulty breathing, swelling of your face, hands, lips, tongue, or throat

Infections that are fatal and often deadly could occur while using everolimus. Take this medicine off your list and contact your physician whenever you show symptoms of infection, such as chills, fever, or swollen glands. Flu-like symptoms.Zortress can trigger an enlargement of the blood vessels in your transplanted organ. This is especially true within the first 30 days following transplant. Contact your doctor immediately if you notice the following symptoms: nausea, fever, vomiting, the presence of blood or urine in your system, dark urine, no or little urinary frequency, or pain in your stomach, in the groin area, the lower back, or in the side.

See your doctor right away. If you suffer from:

  • New or worsening cough, wheezing, and breathing issues;
  • The appearance of redness, heat, or a swell, and a slow or no healing cut or surgical incision
  • Simple bleeding, unusual bruises;
  • Blood sugar levels are high. Thirsty, urination frequency, dry tongue, refreshing breath smell, headache, blurred vision,
  • Red blood cell count is low (anemia): pale skin, unusual tiredness, feeling lightheaded or weak of breath, cold feet and hands.

Common Zortress side effects can include:

  • Swelling in your ankles, legs, or feet;
  • Anemia, infections;
  • Problems with urination;
  • Hypertension of the blood due to elevated cholesterol or triglycerides
  • Nausea, stomach pain, diarrhea, constipation, stomach pain, nausea

This isn't an exhaustive list of possible side effects, and others could happen. Consult your physician to seek medical advice on adverse effects. You can report any side effects to the FDA at 1-800-FDA-1088.

Interaction with other drugs

Many medications can interact with everolimus. There are many possible interactions that are not mentioned in this article. Inform your doctor of all the medications you are currently taking and any that you decide to start or stop using, in particular:

  • Cyclosporine and other medicines to avoid the risk of organ donation rejection;
  • John's wort;
  • As an antimicrobial or antifungal medicine.
  • Medications for cholesterol;
  • Heart or blood pressure medication;
  • HIV medicine;
  • Seizure medicine;
  • Tuberculosis

This is not a complete list, and other drugs may interfere with everolimus. This includes over-the-counter and prescription medications, vitamins, and herbal supplements. The list of possible drug interactions is not exhaustive. Are listed here.

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