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Generic name: cholecalciferol (vitamin D3) [KOE-le-kal-SIF-e-role]

Brand names: Carlson D, Ddrops, Decara, Delta D3, Enfamil D-Vi-Sol,… show all 10 brands
Drug class: vitamins

What is Replesta?

Vitamin D3 is cholecalciferol. Vitamin D is essential for calcium absorption.Cholecalciferol can be used to supplement the diet of people who don't get enough vitamin D.Cholecalciferol can be used in other ways not mentioned in this guide.

Side effects of Replesta

If you experience any of the following symptoms of an allergic reaction, seek immediate medical attention: hives, difficulty breathing, swelling of the face, lips, or throat.

If you experience:

  • Chest pain and feeling short of breath
  • Growth problems in children taking cholecalciferol; or
  • Early signs of a vitamin D overdose include weakness, weight loss, muscle or bone pains, constipation, and vomiting.

Some side effects may be milder or even non-existent.There may be other side effects. For medical advice on side effects, call your doctor.To report adverse effects, you can contact the FDA at 1-800-FDA-1088.


If you are allergic to vitamin D, have high calcium or vitamin D levels in your blood, or if your body has a condition called malabsorption, you should avoid taking cholecalciferol.

Before you take this drug

If you are allergic to vitamin D or have any of the following:

  • Hypervitaminosis () D;
  • Hypercalcemia is a condition where there are high calcium levels in the blood.
  • Malabsorption is a condition where your body has difficulty absorbing nutrients from food.

Inform your doctor if you experience any of these symptoms:

  • Heart disease
  • Kidney disease
  • An electrolyte imbalance.

You should consult your doctor before using cholecalciferol if you have allergies, diabetes, or phenylketonuria (PKU). Before using cholecalciferol, consult your doctor if you suffer from allergies, diabetes, or phenylketonuria.If you are breastfeeding or pregnant, consult your doctor before taking cholecalciferol. You may need a different dose during pregnancy or breastfeeding.Do not give cholecalciferol without consulting a doctor. The dose your child receives will vary depending on their age, weight, diet, and other factors.

How to take Replesta?

Read all the instructions and directions that come with your prescription. Only use the recommended dosage of cholecalciferol.You can take cholecalciferol with or without food.Does liquid cholecalciferol with care. Use the provided dosing syringe or a medicine dosage measuring device (not a spoon).Chew the chewable tablet before swallowing it.Place the disintegrating tablet (Quick Melt) on your tongue. Do not swallow it whole. Let it dissolve in your mouth without chewing. You can drink liquids to help you swallow the tablet.You should only take the cholecalciferol tablet once a week or once a month. Be sure to follow your doctor's instructions. You must chew the wafer before swallowing it.You will be required to have frequent blood tests while using cholecalciferol. You may need to have x-rays.How long you will be treated with cholecalciferol by your doctor is determined by him.Cholecalciferol is only one part of an overall treatment plan that may also include dietary changes, calcium and vitamin supplementation, and other treatments. You should follow your doctor's advice.Find out what foods to eat in order to get enough vitamin D and calcium. You may need to adjust your cholecalciferol dosage as you change your diet.Keep away from heat and moisture. Store at room temperature.

What happens if I miss the dose?

Take the missed dose as soon as you can. Skip the missed dose when your next dose is near. Never take two doses in one go.

What happens if I overdose?

Call the Poison Help Line at 1-800-222-1222 or seek emergency medical care. A vitamin D overdose can have serious and life-threatening effects.Overdose symptoms include nausea, vomiting, loss of appetite or thirst, urinating less or more than usual, stiffness, or body aches.

What should be avoided?

Before taking any antacids, multivitamins, or mineral supplements while taking cholecalciferol, consult your doctor or pharmacist.

Interaction with other drug

Take your other medications at least two hours before or after taking cholecalciferol.Other drugs, such as vitamins and herbal remedies, may also affect cholecalciferol. Tell your doctor about all medications you take, including those you start or stop using.