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Generic Name: Vinorelbine vin-OR-elbeen vin-OR-elbeen [vin-OR-el-been]
The Class of Drug: Mitotic inhibitors

What is Navelbine?

Navelbine is a treatment for non-small-cell lung cancer. Sometimes, it is used in conjunction with other cancer treatments.Navelbine could be used for additional reasons not covered in this guideline.

Side effects of Navelbine

Contact a medical professional immediately. Get medical attention immediately if you notice symptoms that indicate an allergic reaction, such as hives, difficulty breathing, and swelling of your lips, face, and tongue.

Navelbine can cause serious adverse reactions. Consult your doctor immediately if you suffer from:

  • Extremely constipated, nausea, severe constipation, bloody or black stools
  • Numbness, tingling, and muscle weakness;
  • Discomfort, redness, and peeling of the skin on the feet and hands;
  • A new or worsening new or worsening cough, wheezing, chest tightness, difficulty breathing;
  • Dark urine; jaundice (yellowing of the eyes or skin);
  • Discomfort, burning, or changes in the skin after the injection was administered,
  • Low blood cell count low blood cell counts: fever, chills, fatigue, mouth sores, skin sores, simple bruising, unusual bleeding, pale skin, cold feet, and hands being lightheaded or sluggish.

Consult your doctor about methods to avoid severe constipation during treatment with Navelbine.

Common negative side effects of Navelbine could include:

  • Nausea, vomiting, and constipation;
  • Weakness;
  • Numbness or tingling sensations in your feet or hands;
  • Low blood cell count;
  • Abnormal tests of liver function;
  • Bleeding, redness, pain, or irritation on or around the needle.

This is not an exhaustive listing of all negative side consequences. There are other side effects that could happen. Ask your doctor for medical advice about the consequences. If you experience any side negative effects to the FDA by calling 1-800-FDA-1088.


You could contract infections more often, including severe or fatal illnesses. Call your doctor when you experience an illness that causes chills, fever, fatigue, skin sores, coughing, bleeding, pale skin, abnormal bleeding, or difficulty breathing.

Before you take this drug

It is not recommended to treat with Navelbine in the event that you are allergic to it or if you suffer from severely low white blood cells.

Speak to your doctor if you have ever suffered from:

  • Liver disease;
  • Bone marrow suppression
  • A nerve disorder;
  • Radiation therapy and other treatments for cancer.

Navelbine could cause harm to an unborn baby and cause a birth defect when the father or mother is taking it.

  • If you're female, you may need to pass a negative pregnancy test before beginning this treatment. Don't use Navelbine if you are expecting. Utilize the most effective contraception to stop pregnancy while using this medicine and for at least six months after the last dose.
  • If you're male, use effective birth control if you have a partner who can get pregnant. Continue using birth control for a minimum of 3 months after the last dose.
  • Contact your physician immediately if you notice a pregnancy during the time that both the mother and father are taking Navelbine.

Navelbine may damage sperm and make it harder for you to become pregnant when you are taking the drug. It is still recommended to take birth control in order to prevent pregnancy since the medication could cause harm to a baby who is not yet born.

It is not recommended to breastfeed while taking Navelbine or for a minimum of 9 days following the last dose.

How to take Navelbine?

Navelbine is administered in the form of an infusion into the vein. Your healthcare provider will offer you the injection.Navelbine is generally administered each day for a period of seven days to six weeks. The frequency of your treatment will be determined by the illness being treated. Follow your doctor's dosage instructions with care.

Inform your doctor if you experience any burning, pain, or swelling in the area of your IV needle after Navelbine is injected.

Navelbine influences the immune system. It can cause you to contract infections more frequently, including deadly infections. Your blood needs to be checked regularly, and treatment could be delayed based on the result.

What happens If I miss a dose?

Consult your physician for further instructions in the event that you don't make an appointment to see your nurse.

What happens If I overdose?

For medical emergencies, seek emergency medical attention or contact the Poison Help line at 1-800-222-1222.

The signs of an overdose could include white spots or sores in your throat or mouth, as well as painful swallowing, heartburn, severe constipation, and stomach pain.

What should be avoided?

Do not get a "live" vaccine while using Navelbine, and stay clear of coming into contact with anyone who has recently been exposed to a live vaccine. There is a risk that the virus may be passed to you. Live vaccines comprise measles, mumps, measles, rubella (MMR), rotavirus, typhoid, yellow fever, varicella (chickenpox), and zoster (shingles).

Interaction with other drugs

There are times when it's not recommended to take certain medications simultaneously. Certain medications can alter the blood levels of other medications you are taking, which could cause more side effects or make the medication less effective.

A variety of drugs can have an effect on Navelbine. This includes prescription as well as over-the-counter medications, vitamins, and herbal remedies. The interactions between these products are not mentioned here. Inform your doctor of all the medications you are currently taking as well as any new medications you are about to start or stop taking.