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What is Efavirenz Lamivudine and Tenofovir?
Efavirenz, lamivudine, and tenofovir are antiviral drugs for treating human immunodeficiency virus (HIV). HIV is a virus that can trigger acquired immunodeficiency disorder (AIDS). Lamivudine, efavirenz, and tenofovir do not provide an effective cure for HIV or AIDS.Symfi is intended for adults and children who weigh a minimum of 88 pounds (40 kg).Symfi L is intended for the adult and child with a weight of at least 77 lbs (35 kgs).Efavirenz, as well as lamivudine and tenofovir, could be used for other purposes not mentioned in this medication guide.
Side Effects of Efavirenz Lamivudine and Tenofovir
Contact emergency medical assistance. If you notice symptoms that indicate an allergic reaction (hives or breathing difficulties and swelling in your throat or face) or an extreme skin reaction (fever and burning sensations around your eyes, pain in the skin, and the skin is red or purple, which spreads and leads to blisters as well as peeling),
Efavirenz, lamivudine, and tenofovir could result in serious adverse reactions. Contact your physician immediately if you experience severe dizziness or drowsiness, difficulty focusing, or odd dreams;
- Severe dizziness or drowsiness, trouble concentrating, strange dreams;
- Issues with thinking, confusion thinking problems, hearing or seeing things that don't exist (may take months to years after starting taking this medication);
- Rapid or pounding heartbeats, a chest that is fluttering, and dizziness that is sudden (like you'd be snoring);
- Difficulties with balance and coordination issues;
- New or worsening bone pain,
- The pain in your legs, arms, or hands;
- Lactic acidosis: muscle pain, difficulty breathing, stomachache and vomiting as symptoms; irregular heartbeat rate; dizziness; feeling cold or weak or fatigue are also indicators.
- Pancreatitis—severe discomfort in your upper stomach that spreads into your lower back—along with vomiting
- Strange thoughts, such as fear, paranoia, and despair thoughts of harming you or others;
- Liver issues: swelling around the midsection area, abdomen pains, unusual fatigue, and loss of appetite.black stools, dark urine and jaundice (yellowing of eyes or skin).
Symfi can affect your immune system and cause some adverse reactions (even months or even weeks after taking the medicine).Inform your physician immediately if you experience:
- Symptoms of a new infection: fever, night sweats, swollen glands, and cold sores coughing, wheezing, diarrhea, weight loss
- Difficulty swallowing or speaking issues with balance or eye movement and prickly or weak feeling trouble swallowing, balance or eye movement problems;
- Swelling in your throat or neck (enlarged thyroid), menstrual cycles, impotence
Common adverse effects of efavirenz, lamivudine, and tenofovir can be:
- Headache, dizziness;
- Depression and thinking issues;
- Nausea, diarrhea;
- Sleep problems (insomnia);
- Pain;
- Weakness, tiredness;
- Congestion, a stuffy nose, and sinus pain
- It can be a rash
- Change in the appearance or shape of fat (especially the body, legs, facial, and neck), the breasts, your waist, and your neck).
This list does not represent all possible side effects; other ones could arise. Please consult your physician regarding possible effects, or report them directly to FDA at 1-800-FDA-1088.
Similar or related drugs
Biktarvy, Descovy, Truvada, Tenofovir, Atripla, Complera, and Stribild
Warnings
If you've ever suffered from hepatitis B,Potential complications could cause birth defects to the unborn baby or cause harm. It is possible that you will require regular liver function tests over many months.Do not change the dose or cease taking the medication without consulting your physician.
Prior to using this drug
This medicine:
- Also, you can take elbasvir as well as grazoprevir (for hepatitis C) and
- You're allergic to any combination medication that contains efavirenz, lamivudine, tenofovir.
Speak to your physician immediately if you suspect any symptoms of:
- The liver condition (especially hepatitis B and C)
- Renal disease (or if you're taking dialysis);
- Heart-related problems;
- The long QT disorder (in the case of you or a member of your family);
- Addiction to alcohol or drugs.
- A seizure;
- Fractures or other issues related to your bones.
It is possible to suffer from a condition known as lactic acidosis. It is a risky buildup of lactic acid in your blood. It is more likely if you're obese or female. Talk to your doctor about the risk.You might need to undergo an ultrasound test that is negative prior to beginning this treatment.Do not take this medication if you are expecting. It could harm the unborn baby or cause birth defects. Utilize effective contraception to stop pregnancy while taking this medication and for a minimum of 12 weeks following your last dose.Utilize two birth control methods to avoid pregnancy, such as a barrier type like a condom cervical cap, a diaphragm, or a contraceptive sponge.If you're expecting and are a registered mother, your name could be included on an OB-GYN registry to track how this medication affects your baby.Women who have HIV or AIDS shouldn't breastfeed babies. Even if your child is born with no HIV, it is possible that the virus will be transmitted to your baby by the milk you give them.
How to take Efavirenz Lamivudine and Tenofovir?
Follow all instructions listed on your prescription label, as well as reading all medication guides and instructions.Follow the medication precisely as directed.Efavirenz, as well as lamivudine and tenofovir, form an entire regimen that should not be combined in conjunction with other antiviral medicines.Use this medicine with a full stomach before going to bed.You'll require regular medical examinations.Do not alter the dose or frequency of your dosing without consulting your physician. Anyone suffering from HIV should be under the supervision of a physician.Keep this medicine in its original bottle at room temperature and away from heat and moisture.If you've had any experience with the virus hepatitis B, it is possible that the virus will get more active or worse during the time following you stop taking the medicine. It is possible that you will require regular liver function tests for a few months following the last dose.
Details on dosage
Usual Adult Dose for HIV Infection:
1 tablet, orally, once a day
Use as a complete treatment to treat HIV-1 infection.
Usual Pediatric Dose for HIV Infection:
1 tablet taken orally every day
Comments:
Symfi LoTM has been approved by the FDA for people with a weight of at least 35 kg.
SymforM has been approved by the FDA for people with a weight of more than 40 kilograms.
Recommended for children who are able to swallow solid tablets
Use as a complete treatment to treat HIV-1 infection.
What happens if I miss the dose?
You should take the medication as quickly as you are able, but do not take your missed dosage if you are nearing the time to take the next dose. Don't take two doses at a time.Refill your prescription prior to the expiration date of your medication.
What happens if I overdose?
For medical emergencies, seek emergency medical attention or contact the Poison Help Line toll-free at 1-800-222-1222.
What should be avoided?
Beware of eating or drinking any drink that contains the ingredient sorbitol (an artificial sweetener).Avoid driving or engaging in hazardous activities until you are aware of the effects this medicine has on your body. The way you react could be affected.
Interaction with other drugs
It is sometimes not safe to take certain medications in combination. Certain drugs may affect the blood levels of other medications you are taking, which could create side effects or render the drugs less effective.A variety of medications can interact with efavirenz, lamivudine, and tenofovir. This includes prescription and over-the-counter drugs, vitamins, and herbal supplements. There are not all the interactions mentioned here. Inform your doctor of all the medications you are currently taking as well as any new medications you are about to start or stop taking.