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Name of generic: efavirenz, an emtricitabine-based drug, and Tenofovir ([ef-AV-ir-enz, emtricitabine ef-AV, em, trye-SYE, and ten-of-oh-vir Tenofovir
Drug class: antiviral combinations

What is Atripla?

Atripla includes a mix consisting of the drugs efavirenz, emtricitabine, and tenofovir. Efavirenz, as well as emtricitabine and tenofovir, are all antiviral drugs that stop the human immunodeficiency virus (HIV) from reproducing in your body.Atripla is a treatment for HIV, a virus that causes acquired immune deficiency syndrome (AIDS). It is not the cure to treat HIV as well as AIDS.Atripla is intended for adults and youngsters who are 12 years old and weigh at least 88 lbs (40 kg).


Do not use Atripla along with Adefovir, Atazanavir, Voriconazole, or any other medication that contains emtricitabine, lamivudine, or tenofovir.Inform your doctor about all your medications and all the ones you begin or stop taking. A variety of drugs interact, and certain drugs shouldn't be taken together.Atripla could cause serious or fatal liver issues. Call your doctor immediately if you experience symptoms like stomach swelling, pain, or loss of appetite. discoloured urine or yellowing of your eyes or skinAtripla could trigger a dangerous disease known as lactic acidosis, which is a serious accumulation of lactic acid inside your blood. Consult your doctor or seek urgent medical assistance when you experience strange muscle pains, difficulty breathing or stomach pains, dizziness, feeling cold, fatigued, or weak.If you've had hepatitis B or C, it could be active or worsen after quitting Atripla. You could require regular liver function tests over time.

Similar/related drugs

Biktarvy, Descovy, Truvada, Tenofovir, Emtricitabine, Lamivudine, and Zidovudine

Prior to using this drug

You shouldn't use Atripla in the event that you are allergic to the drugs efavirenz (Sustiva), emtricitabine (Emtriva), or tenofovir (Viread).Do not consume Atripla along with adefovir, atazanavir, voriconazole, or any other medication that contains lamivudine, emtricitabine, or tenofovir (such as Combivir, Complera, Descovy, Epivir, Epzicom, Genvoya, Odefsey, Stribild, Trizivir, Truvada, or Vemlidy).

To be sure Atripla is not harmful to you, inform your doctor if you are suffering from:

  • Kidney disease or liver failure;
  • Long qt syndrome;
  • Mental illness, taking antipsychotic medication, or injecting drugs;
  • Epilepsy or any other seizures;
  • Low bone mineral density;
  • Hepatitis b as well as c infection

It is possible to be diagnosed with an illness called lactic acidosis. This is an extremely dangerous accumulation of lactic acid in your blood. This is likely if you suffer from other medical issues, if you've been taking HIV medication for a prolonged period of time, or if you are female. Talk to your doctor regarding your chances of being at risk.Efavirenz, emtricitabine, and tenofovir are known to create birth defects. Avoid using Atripla in the case of pregnancy, and don't become pregnant for a minimum of 12 weeks after stopping taking this medication.Atripla can cause hormonal birth control to become less effective, which includes contraceptives, birth control injections, skin patches, implants, or vaginal rings. To avoid pregnancy when using Atripla, make sure you make use of a barrier type of birth control, such as a condom, diaphragm, cervical cap, or contraceptive sponge.Women suffering from HIV or AIDS shouldn't breastfeed infants. Even if the baby is born with no HIV, it is possible that the virus will be transmitted to your baby by the milk you give it.

How do I take Atripla?

Use Atripla exactly as directed by your physician. Follow the instructions on your prescription label, and go through all the medication guides or instructions sheets.Take this medication with a full stomach and a cup of fluid.You'll need to take regular medical tests.This medication could affect the urine test for drug screening and cause incorrect results. Inform the lab staff that you are taking efavirenz, tenofovir, and emtricitabine.Storage Atripla within the bottle at room temperature and away from heat, moisture, and light. Make sure the bottle is tightly sealed when not in use.If you've had any experience with hepatitis B, the virus could become active or worse during the time following you stop taking Atripla. It is possible that you will require regular liver function tests when taking this medication and for a few months following the last dose.

Info on dosage

Usual Adult Dose of Atripla to Treat HIV Infection:

1 tablet taken orally every day
Utilise: as a full regimen or in combination with other antiretroviral agents to aid in treatments for HIV-1

Usual Adult Dose of Atripla for Nonoccupational Exposure:

US CDC recommendations: 1 tablet taken orally every day
Therapy duration Duration of therapy: 28 days
The components of this medication are recommended as a recommended NNRTI-based treatment for postexposure prophylaxis that is not a result of work. HIV disease.
It is recommended to begin the treatment immediately and within 72 hours after exposure.
Current guidelines should be reviewed for further details.

Usual adult dose of Atripla for occupational exposure:

US Public Health Service working group recommendations 1 tablet taken orally, every day
The duration of therapy is at least 28 days if it is tolerated
With expert advice, a different regimen can be considered for HIV prophylaxis after exposure.
The treatment should begin as soon as is possible and preferably within a few hours of the exposure.
The optimal time for prophylaxis is not known and could vary based on the protocol of the institution.
Current guidelines should be reviewed for further details.

Usual Pediatric Dose for HIV Infection:

aged 12 or over with a minimum weight of 40 kg 1 tablet taken orally, at least once per day
Utilise: as a full regimen or in conjunction with other antiretroviral agents to aid in treatments for HIV-1

What happens if I miss the dose?

You should take the medication as quickly as you are able, but do not take your missed dosage if you are close to the time of the next dose. Do not take two doses at the same time.

What happens if I overdose?

Get medical attention immediately or contact the Poison Help Line at 1-800-222-1222. The symptoms of an overdose could be uncontrolled muscle movements.

Aviod this

Avoid driving and other hazardous activities until you are aware of the effects of this medication on your body. The way you react could be impaired.This medicine won't stop your illness from spreading. Be sure to not engage in unprotected sexual sex or share toothbrushes, razors, or razors. Discuss with your physician ways to protect yourself from HIV transmission through sex. Sharing needles for medicine or drugs is not safe for healthy people.

Side effects of Atripla

Contact a medical professional immediately. If you are experiencing indications that you are experiencing an allergic reaction (hives, breathing problems, or swelling in your throat or face) or an extreme skin reaction (fever, sore throat, burnt eyes, irritation, or an ailment that is purple or red with peeling and blisters),The symptoms of mild lactic acidosis could get worse as time passes, and the condition could cause death. Take immediate medical assistance when you experience unusual muscle pain, difficulty breathing, stomach pain, vomiting, dizziness, an irregular heartbeat, or feeling fatigued or weak.

See your doctor right away. If you suffer from:

  • Strange thoughts or behaviours, unusual thoughts or behaviours, anger, depression thoughts of harming you or others; hallucinations;
  • A seizure (convulsions);
  • Kidney issues such as increased thirst and the need to urinate, muscle weakening, or pain;
  • Liver issues, swelling around the middle of your body, right-sided stomach pain, a loss of appetite and dark urine, stool that is coloured with clay, and jaundice (yellowing of the eyes or skin).

Atripla can affect your immune system and could cause adverse reactions (even months or weeks after you've taken the medicine). Inform your doctor whether you suffer from:

  • Symptoms of an infection that is new, such as night sweats, fever, swollen glands, cold sores, cough, wheezing, vomiting, and weight loss;
  • Difficulties swallowing or speaking, issues with balance or eye movement, or weakness or prickly feelings;
  • Swelling in your throat or neck (enlarged thyroid) menstrual fluctuations, impotence

Common atripla adverse effects could be:

  • Fatigue, dizziness, or drowsiness;
  • Nausea, diarrhoea;
  • Headaches, depression, mood swings, and trouble concentrating;
  • Sleep problems (insomnia), strange dreams;
  • It can be a rash
  • Change in the form or position of your body fat (especially the body, legs, facial area, neck, breasts, waist, and neck).

This isn't an exhaustive list of possible side effects, and other side effects could occur. Consult your physician to seek medical advice on the effects. Report any symptoms to the FDA at 1-800-FDA-1088.

Interaction with other drug

There are times when it's not safe to take certain medications simultaneously. Certain drugs may affect the blood levels of other medications that you take, which can create side effects or render the medication less effective.Atripla could affect your kidneys, particularly in conjunction with certain medications to treat cancer, infections, osteoporosis, organ transplant rejection, bowel diseases, high blood pressure, arthritis, or pain (including Advil, Motrin, and Aleve).

Inform your doctor about your current medications. Certain drugs can interfere with efavirenz, tenofovir, and emtricitabine. specifically:

  • John's wort;
  • As an anti-microbial or antifungal medicine
  • An antidepressant
  • Other hiv medications;
  • The cholesterol-lowering medication
  • Heart or blood pressure medications
  • Medication to avoid rejection of organ transplants
  • Medicines to treat hepatitis
  • Seizure medicine;
  • Tuberculosis

This list isn't complete. A variety of drugs may be incompatible with efavirenz, emtricitabine, and tenofovir. Additionally, certain medications should not be taken simultaneously. Discuss with your doctor your current medications as well as any medications you are about to start or stop taking. This includes over-the-counter and prescription medicine, vitamins, and herbal supplements. The interactions between these products are not all included here.




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