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Ibuprofen with pseudoephedrine

Generic name: ibuprofen and pseudoephedrine [EYE-bue-pro-fen-and-SOO-doe-ee-FED-rin]

Brand names: Advil Cold & Sinus, Advil Cold & Sinus Liqui-Gel, Advil Cold and Sinus, Dimetapp Sinus, Dristan Sinus,… Show all 13 brands
Dosage forms: oral capsule (200 mg–30 mg), oral tablet (200 mg–30 mg)
Drug Class: Upper Respiratory Combinations

What is Ibuprofen with pseudoephedrine?

Ibuprofen is a nonsteroidal analgesic drug (NSAID). Pseudoephedrine decongestant.

Ibuprofen combined with pseudoephedrine can be used to treat symptoms such as stuffy noses, nasal congestion, a cough and pain, or a fever due to the flu or common cold.This medication guide does not list all possible uses of ibuprofen or pseudoephedrine.

Side effects Ibuprofen with pseudoephedrine

If you experience symptoms of an allergic reaction, such as sneezing, running or stuffy noses, hives or difficulty breathing, or swelling in the face or throat, or a severe reaction to your skin (fever or sore throat with burning eyes, or skin pain or blistering), seek emergency medical attention.

If any of these symptoms appear, seek immediate medical care.

Ibuprofen can cause serious side effects. If you experience:

  • Dizziness or severe sleepiness
  • Fast, pounding, or uneven heartbeat;
  • Easy bruising and bleeding (nosebleeds or bleeding gums);
  • A skin rash is a rash on the skin, regardless of how mild it may be.
  • Signs of stomach bleeding include bloody or tarry stool, vomiting that looks like coffee, or coughing up blood.
  • Liver problems: loss of appetite, pain in the upper right corner of the stomach, fatigue, itching dark urine, clay-coloured stools, jaundice
  • If you have kidney problems, it could be that your urine is not as frequent, or you are experiencing swelling of the feet or ankles or feeling tired.
  • Nerve problems: fever, headache; neck stiffness; chills; increased sensitivity to the light.

Side effects of ibuprofen or pseudoephedrine include:

  • Diarrhea, constipation;
  • Headache, dizziness, drowsiness, weakness;
  • Upset stomach; nausea; vomiting; loss of appetite
  • Feeling anxious or excited
  • Sleep problems (insomnia);
  • Flushing (warmth, redness, or tingling feeling)

There may be other side effects. For medical advice regarding side effects, call your physician. To report side effects directly, the FDA can be reached at 1-800-FDA-1088.

Warnings

Ibuprofen may increase the risk of a fatal stroke or heart attack. This medicine should not be taken before or immediately after heart bypass surgery.Ibuprofen may lead to fatal stomach or intestinal bleeding.

Before you take this drug

Ibuprofen may increase your risk of a fatal heart attack or stroke even if there are no risk factors. Ibuprofen or pseudoephedrine should not be taken before or after coronary artery bypass graft surgery (CABG).

Ibuprofen can also cause fatal stomach or intestinal bleeding. You may not be aware of these conditions if you use ibuprofen or pseudoephedrine. This is especially true for older adults.This medicine should not be used if you're allergic to ibuprofen, pseudoephedrine, or have had an aspirin attack.

If you've taken an MAO inhibitor within the last 14 days, don't take ibuprofen or pseudoephedrine. A dangerous drug interaction may occur. MAO inhibitors are isocarboxazid (linezolid), methylene blue injection, phenelzine, and tranylcypromine.

Never give ibuprofen or any other pain reliever to a child under 12 years of age.

If you have had any of the following:

  • Heart condition, high blood tension, high cholesterol, diabetes, or if you are a smoker.
  • A heart attack, stroke, or blood clot
  • Stomach ulcers or bleeding
  • Asthma;
  • Liver or kidney disease
  • A thyroid disorder
  • Diabetes
  • Urination problems, enlarged prostate

Nsaids should only be taken by pregnant women with the approval of their doctor. Nsaids can cause kidney or heart problems for the baby, as well as pregnancy complications.

Consult your doctor before taking this medication if you're breastfeeding.

How to take Ibuprofen with pseudoephedrine?

Follow the directions on the package or those prescribed by your physician. Overdosing on ibuprofen may cause damage to your stomach and intestines.This medicine can help reduce stomach upsets.

If you experience a prolonged fever, new symptoms, or your condition doesn't improve after 7 days of taking the medication, call your doctor.Tell the surgeon if you've taken this medication within the last few days.Store away from heat and moisture at room temperature.

Details on dosage

Adult dose for sinus symptoms:

Take one caplet or liquid-filled capsule of 200 mg ibuprofen or 30 mg pseudoephedrine every 4 to 6 hours while symptoms persist.
If symptoms are not improved by one cap, you may use two caps.
Maximum dose: 6 caps per 24-hour period
Comments:
Do not exceed the recommended dosage.
Use the lowest effective dose.

The usual pediatric dose for sinus symptoms:

Caplets containing 200 mg of ibuprofen and 30 mg of pseudoephedrine or liquid-filled capsules
12 years of age and older: Take 1 cap every 4 to 6 hours while symptoms persist.
If symptoms are not improved by one cap, you may use two caps.
Maximum dose: 6 caps per 24-hour period
Comments:
Do not exceed the recommended dosage.
Use the lowest effective dose.

What happens if I miss the dose?

You may not have a schedule for ibuprofen or pseudoephedrine, as they are used only when necessary. If it is almost time to take your next dose, skip the missed dose. Never take two doses in one go.

What happens if I overdose?

Call 1-800-222-1222 for poison help or seek immediate medical attention.Overdose symptoms include nausea, vomiting, diarrhea, ringing of the ears, agitation, and sweating. Other symptoms are blood in your cough, shallow or weak breathing, fainting, or seizures (convulsions).

What should be avoided?

Avoid alcohol. Alcohol can increase the risk of stomach bleeding.Before using any other cold or cough medicines, ask your doctor or pharmacist if they contain similar ingredients.

Interaction with other drug

If you are taking an antidepressant, ask your doctor if it is safe to take ibuprofen or pseudoephedrine. Certain antidepressants may cause bruising and bleeding.

Before using ibuprofen or pseudoephedrine in conjunction with other medications, ask your doctor or pharmacist.

  • Lithium;
  • Methotrexate;
  • A blood thinner (Warfarin Coumadin Jantoven)
  • Heart or blood pressure medications, including diuretics or "water pills";
  • Steroid medicine (such as prednisone).

This list is incomplete. Ibuprofen, pseudoephedrine, and other drugs can interact with each other. This includes prescription and over-the-counter medicines, vitamins, and herbal products. This list does not include all possible drug interactions.