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Abelcet

Generic name: amphotericin B lipid complex [ AM-foe-TER-i-sin-B-LIP-id-KOM-plex ]

Drug class: Polyenes

What is Abelcet?

Abelcet is an antifungal medication used to treat severe, potentially life-threatening fungal illnesses that are not treatable by other antifungal drugs.

Abelcet is also employed for other purposes not covered in this medication guide.

Side Effects of Abelcet

See a doctor immediately. Get medical attention if you notice symptoms that indicate an allergic reaction, such as hives, difficulty breathing, or swelling of your lips, face, and tongue.

Specific side effects can occur after the injection. Inform your doctor immediately when you experience a fever, lightheaded, shaky, weak, or short of breath.

Abelcet may cause serious side effects. Consult your doctor immediately If you suffer from the following:

  • New or worsening cough, wheezing, trouble breathing;

  • Blue lips, blue-colored fingers or toes;

  • Easily bleeding, unusual bruising, or red spots on the skin

  • Slow heart rate, weak pulse, fainting breath, slow breathing (breathing could be stopped);

  • kidney problems: no or little urinary frequency, swelling in your ankles and feet, being exhausted or sluggish and

  • low calcium level - muscle spasms or contractions and tingling or numbness;

  • Low magnesium, dizziness which is irregular and heartbeats, feeling jittery, muscle cramps, muscle spasms, cough, and choking feeling. 

  • Lower potassium level, leg muscle cramps, constipation, heart flutter, and increased thirst or urination—muscle weakness or a feeling of limpness.

Common adverse effects of Abelcet could include:

  • Fever, chills;

  • Nausea, vomiting; or

  • Abnormal tests of kidney function.

This isn't an exhaustive list of all side effects. Others could happen. Contact your doctor to seek medical advice on the impact. You may report any adverse reactions to the FDA at 1-800-FDA-1088.

Warnings

Inform your family members whether you are feeling ill or lightheaded or feel weak in your breath when you're receiving Abelcet.

We highly recommend you to Consult with the doctor before taking this medicine. 

You shouldn't be treated using amphotericin B If you are allergic to it.

Inform your doctor if you have ever suffered from the following:

  • kidney disease;

  • A blood cell transfusion or

  • The imbalance of electrolytes (such as low or high levels of magnesium or potassium or magnesium in the blood).

It isn't known if this medication will cause harm to a baby who is not yet born. Inform your doctor if you are expecting or planning to be pregnant.

It is not recommended to breastfeed when you are taking Abelcet.

What Happens If I Miss a Dose?

If Abelcet is administered during your stay in a hospital, you aren't likely to skip the dose.

If you are taking this medication in the outpatient facility, we recommend you call your doctor for instructions if you have not made an appointment to get the Abelcet injection. 

What Happens If I Overdose?

Since Abelcet is prescribed by a medical professional in the medical environment, it is not likely for an overdose to occur.

What Should be Avoided?

Follow the instructions of your physician regarding any limitations on foods, drinks, or any activity.

Interaction with Other Drugs

Amphotericin B could cause kidney damage, particularly when taking certain medications for osteoporosis, cancer, infections, organ transplant rejection, intestinal issues, high blood pressure, or arthritis pain (including Advil, Motrin, and Aleve).

You must need to inform your doctor if to take these other medication that are listed below:

  • Corticotropin (ACTH);

  • Digoxin, digitalis;

  • Zidovudine;

  • Other antifungal medicine--clotrimazole, fluconazole, ketoconazole, miconazole; or

  • Steroid medicine--dexamethasone, prednisone, methylprednisolone, and others.

This list needs to be more comprehensive. Other medications can affect Abelcet, which include prescription and over-the-counter medicines, vitamins, and herbal products. Some interactions with drugs are not listed here. They are listed here.

 

DRUG STATUS

Availability

Prescription only

Pregnancy & Lactation

CSA Schedule*

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