The Web Health


Abacavir and Lamivudine

The name of the generic Abacavir and Lamivudine

Name of Brands: Epzicom

Format for Dosage: Tablet

Drug classification: Antiretroviral Agent, Nucleoside Reverse Transcriptase Inhibitor (NRTI) Combination

What's the difference between Abacavir in comparison to Lamivudine?

Abacavir and Lamivudine are incorporated into a tablet that creates an antiretroviral medicine that can be fixed and dosed to treat HIV (Human Immunodeficiency Virus) disease. Abacavir and Lamivudine belong to the category of medications called nucleoside reverse transcriptase inhibitors (NRTIs), which are used together to stop the spread of HIV.


  • As with Abacavir on its own, severe and possibly fatal hypersensitivity reactions may occur when combined with Lamivudine. Before starting treatment, a genetic examination is advised to determine people at risk of developing the reaction.
  • Hypersensitivity reactions may manifest as symptoms like fever, nausea, rash, and abdominal pain.
  • Stop the medicine immediately. Do not reintroduce when a hypersensitivity reaction is suspected.

Before You Start this medication:

Before starting Abacavir or Lamivudine, health care providers  of any medical condition you may have, such as liver disease, kidney disease, or medication allergies.

How to Take Abacavir and Lamivudine?

  • Abacavir and Lamivudine can be consumed orally in one tablet daily, either in combination with or without food, according to your physician's prescription.
  • Be sure to follow your doctor's advice concerning Dosage and time.

Specifics on Dosage

our physician decides the dose of Abacavir and Lamivudine according to factors like your health history, weight, and any other medication you might take.

What Happens if I Don't Take a Dose?

If you miss a dose, take it when you can remember. But if you're nearing the time to take your next dose, you can skip the missed dose and follow the regular dosing schedule.

What Happens if I Overdose?

If you suspect that you have overdosed, get medical help immediately. Some of the symptoms associated with an overdose include vomiting, nausea, fatigue, and difficulty getting to sleep.

What Should be Avoided?

  • Avoid stopping Abacavir and Lamivudine without consulting with your doctor since it may cause a reduction in the efficacy of your HIV treatment.
  • Please do not drink alcohol when taking the medication, as it can increase the likelihood of a negative side effect.

Acute Side Effects Abacavir, as well as Lamivudine: Mild Side Effects Commonly, moderate side effects could be:

  • Nausea
  • Headache
  • Diarrhea
  • Fatigue

Adverse effects: Serious adverse effects could be a result of:

  • Hypersensitivity reaction (fever, itching, rash, nausea, vomiting, abdominal discomfort)
  • Lactic acidosis (unusual muscles pain, trouble breathing, or stomach discomfort)
  • Liver problems (jaundice, dark urine, abdominal pain)

Interaction with Other Drugs

Inform your physician about any medicines you take that are not prescription drugs or herbal supplements. Abacavir and Lamivudine can be incompatible with other drugs, specifically those that affect the kidneys or the liver.