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Generic Name: Alpha 1-proteinase inhibitor [AL-fa-1-PRO-tee-nase-in-HIB-i-tor]
The Class of Drug: Miscellaneous respiratory agents

What is Zemaira?

Zemaira is a source of Zemaira, which contains the amino acid alpha-1 proteinase, which is also known as alpha-1 antitrypsin. The protein is naturally found in the body and is crucial to preventing the breakdown of lung tissue.For those who are deficient in the protein alpha-1 antitrypsin, the breakdown of lung tissue can result in the condition known as emphysema (damage in the air sacs that line the lung).

Zemaira can be used to treat alpha-1 antitrypsin deficiency in patients who suffer from symptoms of emphysema.The deficiency of alpha-1 antitrypsin is an inherited condition, and Zemaira cannot treat this condition.


You shouldn't take Zemaira. If you've ever experienced an allergic reaction to alpha-1 proteinase inhibitors or if you suffer from an IgA (immunoglobulin A) deficiency or antibodies against IgA,Zemaira should be mixed with a liquid (diluent) prior to giving it in the form of an injection. If you're taking infusions at home, make sure you know how to prepare and store your medication.

Consult your physician immediately if you experience an adverse reaction that is serious, like chills, fever, body aches, mouth sores, burning or pain when you vomit or wheeze, chest pain or tightness, breathing problems, or changes in your vision. Zemaira is derived by removing the blood plasma of humans (part of the blood), which could be contaminated with infections and viruses. The plasma donated is examined and treated to lower the possibility of it containing infectious agents; however, there is a chance that it can carry the disease. Consult your physician about the dangers and benefits of this treatment.

Before you take this drug

It is not recommended to apply Zemaira if:

  • You've experienced a severe reaction to an alpha-1 proteinase inhibitor.
  • You have an iga (immunoglobulin A) deficiency or antibodies against iga.

To ensure that Zemaira is appropriate for you, consult your physician if you suffer from:

  • Liver disease liver disease
  • Chronic obstructive pulmonary disease (COPD) or another breathing disorder.

Inform your doctor if you are nursing or pregnant.

Zemaira is not allowed for use by anyone who is younger than

Zemaira is derived from donated human plasma and could contain virus-like agents or other pathogens. Plasma donated to the lab is analysed and treated to decrease the chance of contamination; however, there is an opportunity that it might be a carrier of the disease. Consult your physician about the possibility of danger.

Similar or related drugs

Glassia, Prolastin, Prolastin-C, alpha-1 proteinase inhibitor, Aralast NP

How to take Zemaira?

Use Zemaira exactly as directed by your physician. Follow the instructions on your prescription label and review all medication guides and instruction sheets.Zemaira is injectable into veins, typically once per week.The first dose could be administered in a hospital setting where any adverse consequences can be addressed quickly.

Talk to your pharmacist or doctor. If you're not sure of the procedure for using an injection,Make sure you know how to mix the powdered form of Zemaira using the liquid (diluent) and how to store the mix.Inject it when you're ready to administer it. Contact your pharmacist if the medicine is cloudy, changed color, or has particles.

Do not reuse needles or syringes. Put them in an impervious to puncture "sharps" container and dispose of them in accordance with the laws of your state or municipality. Make sure it is out of range of children and pets.Doses are determined by weight.

Keep Zemaira at a room temperature that is cool and far from heat and moisture. Utilize within 3 hours following mixing.Do not store Zemaira in a freezer, and don't use it beyond its expiration date. deadline for expiration on the medicine's label.Dispose of the bottle after a single use, regardless of whether there is remaining medicine inside.

Details on dosage

Usual Adult Dose for Alpha-1 Proteinase Inhibitor Deficiency:

60 mg/kg intravenously every week
Dose-ranging studies that use efficacy criteria have not been conducted.
Use: Continuous treatment for maintenance and augmentation in adults who have medical evidence of emphysema owing to a hereditary defect in alpha-1 proteinase inhibitor (alpha-1 antitrypsin in deficit)

What happens if I miss a dose?

Contact your doctor for advice in case you missed a dose.

What happens if I overdose?

For medical emergencies, seek emergency medical attention or contact the Poison Help line toll-free at 1-800-222-1222.

What should be avoided?

Follow the doctor's advice regarding any restrictions on your food, drink, or activity.

Side effects of Zemaira

Seek medical attention immediately in the event that you exhibit symptoms indicating that you are experiencing an allergic reaction. Zemaira: hives or rash; confusion or feeling lightheaded; fast pulses; chest pain; difficulty breathing; swelling of your lips, face, or tongue

Your doctor might also recommend carrying Epinephrine (Epi-Pen) on hand in case you experience an allergic reaction to Zemaira.Stop taking Zemaira and contact your doctor right away. If you suffer from:

  • Chest pain, wheezing, and difficulty breathing
  • Dizziness, severe headache;
  • A seizure;
  • The sensation of weakness or numbness suddenly in speech, slurred speech, or problems with balance or vision.

You might be a bit faint after your treatment. You may need to rest for a brief time following the

Some common zemaira-related side effects include:

  • Symptoms of a cold like a running nose or stuffy nose, coughing, sneezing, and a sore throat;
  • Headache;
  • Joint or muscle pains;
  • Weakness;
  • Flushing (sudden heat, redness, or a tingly sensation);
  • Nausea;
  • Bleeding or bruising in the area where the medicine was injected.

This is not a comprehensive list of all the side effects. Others could happen. Contact your physician for advice regarding medical effects. You can report any side effects to the FDA at 1-800-FDA-1088.

Interaction with other drugs

Other medications can be incompatible with the alpha-1 proteinase inhibitors, including prescription and over-the-counter medicines, vitamins, and herbal products. Discuss with your physician all other medications you take.