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Generic name: tretinoin topical [ TRET-in-oin ]

Brand names: Altreno, Atralin, Avita, Refissa, Renova, Retin-A, Tretinoin Emollient Topical
Drug class: Topical acne agents

What is Refissa?

Tretinoin helps renew the skin by combining Vitamin A.Refissa is used for acne treatment to smooth out rough facial skin, reduce fine wrinkles, and discolor the skin.Refissa can be used in other ways not mentioned in this guide.

Side effects of Refissa

If you experience any of the following symptoms of an allergic reaction, seek immediate medical attention: difficulty breathing, hives, swelling of the face, lips, or throat.

Refissa may cause serious side effects. If you experience:

  • The skin may experience severe irritation, burning, or stinging.
  • Severe skin dryness;
  • Severe redness, swelling, or blistering.

Refissa may make your skin more sensitive to extreme weather conditions such as wind and cold.

Refissa can cause a number of side effects.

  • Itching, skin redness or burning, and irritation are all symptoms of skin pain.
  • A sore throat
  • The application of the medication may cause mild discomfort or stinging.
  • Changes in the color of treated skin

There may be other side effects. For medical advice on side effects, call your doctor.To report adverse effects, you can contact the FDA at 1-800-FDA-1088.

Similar/related drugs

Topical tretinoin, Retin-A, Renova, Atralin, and Avita


Do not get this medication into your eyes, mouth, or vagina. Also, avoid getting it in the nose creases.

Before you take this drug

Refissa should not be used if you have an allergy to it.Refissa should not be given to children without medical advice. Some brands of topical tretinoin are not recommended for anyone younger than 18.

Inform your doctor if you experience any of these symptoms:

  • Eczema;
  • An allergy fish (the gel can contain ingredients that are derived from the fish).

Refissa is not known to harm unborn babies. Inform your doctor if you are pregnant.You may not be able to breastfeed your baby if you are taking this medication. You should ask your doctor if there are any risks.

How to take Refissa?

Read all instructions or guides that come with your medication and follow all directions. Follow the directions on the label.It will not work faster if you use more or apply it more frequently than recommended. There may be more side effects.Take it only by mouth. Topical medicines are only to be applied topically. Use only on skin that is not sunburned or eczema-affected.Please read and follow all instructions for use that come with your medication. Ask your pharmacist or doctor if you do not understand.Hands should be washed before and after using Refissa. Cleanse and dry the area of skin to be treated before applying. This medicine can cause irritation if applied to wet or greasy skin.After applying Refissa, do not wash or use any other products on the skin for at least an hour.Refissa is best used in conjunction with a comprehensive skin care regimen that includes the use of sunscreen, protective clothing, and avoiding exposure to sunlight.Your skin may not improve for several weeks. Continue to use the medication according to instructions, and inform your doctor if you do not see improvement. Refissa may temporarily worsen your acne if you use it to treat the condition.If your acne doesn't improve in 8–12 weeks or your skin irritation is severe, call your doctor.Even if it doesn't seem to be working, continue taking this medication for the prescribed time.Keep away from moisture and heat at a room temperature.When not in use, keep the bottle tightly shut.Refissa gel is flammable. Avoid using near-open flames or high temperatures. Smoke only after the gel is completely dry.

What happens if I miss the dose?

Skip the missed dose if you're almost due to take your next dose.. Never take two doses of the same medicine at once.

What happens if I overdose?

For poison assistance, call 1-800-222-1222 or get immediate medical help.

What should be avoided?

Avoid tanning beds or exposure to the sun. Refissa may make you more susceptible to sunburn. Use sunscreen with an SPF of 15 or greater when outdoors.Do not get this medication into your eyes, mouth, or vagina. Also, avoid getting it in the nose creases.Avoid skin products that can cause irritation. These include harsh soaps and shampoos, permanent hair dyes or chemicals, hair removal or waxes, as well as skin products containing alcohol, spices, astringents, or lime.Do not use other medications to treat the same areas that you have treated with Refissa, unless you are told by your doctor.

Interaction with other drug

If your doctor has not prescribed otherwise, do not use any skin products containing benzoyl peroxide, sulfur resorcinol, or salicylic acid. These products may cause severe irritation to the skin if they are used in conjunction with Refissa.Other drugs that you take are unlikely to affect the medicine applied to your skin. Many drugs interact with each other. Inform your healthcare providers of all the medicines you take, including vitamins and herbal remedies.