What is Migration?
Gaucher's disease occurs when the body does not have the enzyme required to breakdown certain fats (lipids). The body can become lipid-rich, leading to symptoms like easy bleeding or bruising, anemia, or joint pain. Miglustat can be used by those who are unable to receive enzyme replacement therapy to treat type 1 Gaucher mild-moderate disease. Miglustat can improve the health of your liver, spleen, and bones in Type I Gaucher patients. Nevertheless, miglustat does not cure this disease. This medication guide does not list all possible uses of Miglustat.
Side effects of Miglustat
If you experience any of the following symptoms of an allergy reaction, seek immediate medical attention: difficulty breathing, hives, swelling in your lips, face, throat, or tongue.
Miglustat may cause serious side effects. If you experience:
- Tremors or shakiness, particularly in the hands.
- You may experience numbness or tingling in your feet or hands.
- Weight loss and severe diarrhea.
- Easy bruising (nosebleeds or bleeding gums)
Milustat can cause a number of side effects.
- Gas, constipation, and bloating;
- Nausea, vomiting, stomach pains, indigestions, loss of appetite, and weight loss.
- Dry mouth
- Dizziness, weakness;
- Headache (including migraine);
- Back pain, muscle cramps, leg cramps
- Are your arms and legs experiencing pain? If this is the case for you, treatment options should be explored immediately.
- Memory problems, unsteadiness, feeling out of balance.
- Burning pain on your feet or hands
- Vision problems
- Changes in menstruation patterns
There may be other side effects. For medical advice on side effects, call your doctor. Report any adverse reactions by calling the FDA at 1-800-FDA-1088.
Similar/related drugs
Opfolda, Pombiliti, Zavesca, Cerdelga, Cerezyme, VPRIV, and Eliglustat
Warnings
Please carefully read all instructions printed on your medication's package or label, inform your healthcare providers of any allergies or medical conditions you are suffering from and which drugs you are currently taking.
Before you take this drug
If you have an allergy to miglustat, then it is best not to use the product.
If you've ever:
- Stomach problems;
- Ulcerative colitis is an example of a digestive disorder.
- Kidney disease
- A condition that produces tremors.
Miglustat can harm an unborn child. Prevent pregnancy with effective contraception, and inform your doctor immediately if you fall pregnant. Breastfeeding is not recommended while taking miglustat. This medication should not be given to any person under the age of 18 without consulting a doctor.
How to take Miglustat?
Before taking your medication, carefully read all instructions or guides that come with it and follow them to the letter. As sometimes happens with our health system, doctors can alter dosage amounts; so be sure to take them as prescribed by your healthcare provider. Miglustat should be taken three times per day. The same dose should be taken every day. You will be required to visit your doctor every six months for a checkup on nerve and muscle functions. Blood tests may be required. Avoid heat and moisture at room temperature.
Details on dosage
Adult dose for Gaucher disease:
Normal dose: orally, 100 mg 3 times per day.
Comments:
It has been proven that reducing the intake of foods high in disaccharides, such as lactose and sucrose, and not taking this medication with food can reduce the severity and/or risk of adverse gastrointestinal events.
Due to side effects such as diarrhea or tremor, it may be necessary to reduce the dose to 100mg orally.
Use: When enzyme replacement therapy (e.g., due to hypersensitivity or allergies) is not an option for mild-to-moderate type 1 Gaucher diseases.
What happens if I miss the dose?
Do not take the dose you missed. Use your next dose as usual. Use only one dose at a time. Refill your prescription before it runs out.
What happens if I overdose?
Call 1-800-222-1222 for poison help or seek immediate medical attention.
What should be avoided?
Miglustat may cause serious diarrhea. You may be prescribed anti-diarrhea medication, and your doctor might also suggest dietary changes.
Interaction with other drug
Other medications, such as herbal supplements and prescription medicines, may also affect miglustat. Inform your physician of all medications you are currently taking as well as those you take or start to use, or discontinue.
