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Magnesium gluconate

Generic Name: Magnesium gluconate [mag-NEE-see-um-GLOO-koe-nate].
The Brand Names are: Mag-G, Optimum Magnesium Gluconate, Magtrate, Almora, and Magonate Natal.
Dosage Format: 250 mg and 500 mg oral tablets).
The Class of Drugs: Minerals and electrolytes.

What is Magnesium gluconate?

Magnesium is a natural mineral that occurs naturally. Magnesium plays a role in numerous systems within the body, including the nerves and muscles. Magnesium gluconate is an ingredient used to ensure that magnesium is present in the body. Magnesium gluconate can be used to treat conditions that are not covered in this guide.

Side effects of Magnesium gluconate

Contact a medical professional immediately. If you are experiencing symptoms that indicate an allergic reaction, such as hives, difficulty breathing, and swelling of your lips, face, and tongue. Magnesium gluconate could cause serious adverse side effects. Stop taking magnesium gluconate and contact your doctor immediately if you experience:

  • Confusion, severe drowsiness, feeling like you might pass out.
  • Severe nausea or vomiting.
  • Muscle weakness.
  • Slow heartbeat.

Common side effects of magnesium gluconate include:

  • Diarrhea.
  • Bloating gas.
  • Upset stomach.

This isn't a complete list of possible side effects, and other side effects could be experienced. Consult your physician to seek medical advice on the effects. You can report any adverse reactions to the FDA at 1-800-FDA-1088.

Similar or related drugs

Multivitamin, magnesium oxide, acetylcysteine, biotin, ascorbic acid, niacin, vitamin C.


Follow the directions on your prescription label and on the label of your package. Be sure to inform your health care providers about your allergies, medical conditions, and any other medications you take.

Before you take this drug

Consult a pharmacist or doctor to determine if it is safe to take magnesium gluconate, especially if you have any other medical issues, particularly:

  • Kidney disease.
  • If you are allergic to any of the ingredients.

Talk to your doctor before taking this medication if you are breastfeeding or pregnant. Your dose needs could differ when you are pregnant or breastfeeding.

How to take Magnesium gluconate?

Take it exactly as indicated on the label or as recommended by your physician. Avoid using in larger than smaller quantities or for a longer time than is recommended. In order to help your body more efficiently absorb magnesium gluconate, use the medication before meals or right after you eat. You can take the magnesium gluconate tablet along with a glass of water. Take measurements of liquid medicines using an appropriate dose-measuring spoon or medicine cup. If you don't own a device for measuring doses, ask your pharmacist for one. Keep at room temperature, free of heat, moisture, and light.

Details on dosage

Usual Adult Dose for Dietary Supplement:

500–1000 mg magnesium gluconate (27–54 mg of elemental magnesium) every day, taken orally.

Usual Pediatric Dose for Dietary Supplements:

Recommended intake of dietary supplements (RDA) to take magnesium
From birth to 6 months From birth to 6 months: 30-mg (adequate intake)
7-12 months 7 to 12 months: 75 mg (adequate intake)
From 1 to 3 years Ages 1 to 3: 80 mg
4-8 years 4–8 years: 130 mg
9-13 years: 90 to 13 years:
14–18 years old, male 14 to 18 years, male
14–18 years old Female 14 to 18 years female.
Upper intake limit that is tolerable (UL) for magnesium supplementation:
From 1 to 3 years 1 to 3 years: 65 mg
4-8 years Age range: 4–8 years.
9–18 years old Age range: 9–18 years
Comments: Magnesium gluconate contains 5% elemental magnesium.

What happens if I miss a dose?

You should take the missed dose as quickly as you can remember. Avoid your missed dose if you are close to the time of the next dose. Do not take any additional medicine to make up for the missed dose.

What happens if I overdose?

For medical emergencies, seek emergency treatment or contact the Poison Help Line at 1-800-222-1222. A magnesium overdose could be fatal. The symptoms of an overdose can include slow breathing, loss of consciousness, or coma.

What should be avoided?

Talk to your doctor or pharmacist before you take an antacid, a laxative, or mineral supplements. Many of these supplements contain magnesium. Combining certain items could result in you acquiring excessive amounts of this mineral.

Interaction with other drugs

Magnesium gluconate can cause problems with the body's ability to absorb other medications that you consume by mouth. It can cause certain medicines to be less effective when taken together. Consult your doctor regarding the time you should rest between taking doses of magnesium gluconate and any of these medicines:

  • Antibiotics.
  • Medicine used to treat Paget's disorder of the bone.
  • Osteoporosis treatment.
  • Thyroid medication.

Consult with a pharmacist or doctor to determine if it's appropriate for you to take magnesium gluconate when you're also taking one of the following medications:

  • Calcium hydrate of cellulose.
  • Digoxin.
  • Sodium polystyrene sulfonate.

The lists below are not exhaustive. Other drugs can be incompatible with magnesium gluconate, such as prescription and over-the-counter medicines, vitamins, and herbal products. The interactions of all potential drugs are mentioned in this medication guide.