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Generic Name: Ethinyl estradiol and desogestrel [EH-thih-nill-ess-tra-DYE-ole-and-des-oh-JESS-trel].
Names of Brands: Apri, Azurette, Caziant, Cyred, Cyred EQ.
Drug Class: Contraceptives.

What is Kalliga?

Kalliga is a birth control pill that contains feminine hormones that block the ovulation process (the release of eggs from the ovary). Kalliga can also cause changes to the uterine mucus in your cervical lining, making it difficult for sperm cells to enter the uterus as well as making it harder for fertilized eggs to connect to the uterus. Kalliga is a medicine used to prevent pregnancy. There are several varieties of this medication available. Some brands are not mentioned in this leaflet. Kalliga could be used for other purposes that are not mentioned in this guide.

Side effects of Birth control pills

See a doctor immediately. If you are experiencing symptoms that are warning signs of an allergic response, like hives, trouble breathing, or swelling of your lips, face, and tongue. Birth control pills can result in serious adverse effects. Do not use birth control pills and contact your doctor immediately if you suffer from:

  • Symptoms of a stroke: sudden weakness or numbness, extreme headache and slurred speech. difficulties with balance or vision.
  • Symptoms for a blood clot inside the lung, such as chest pain, a rapid and loud cough or breathlessness, fainting, or bleeding from the chest.
  • Indications for a blood clot that is deep inside the body: pain or swelling within one leg.
  • Heart attack symptoms: chest pressure or pain, expanding into your shoulder or jaw, nausea, sweating.
  • Liver issues: swelling around the midsection area; left-sided stomach discomfort; decreased appetite; dark urine; clay-colored stool; jaundice (yellowing of the eyes or skin).
  • High blood pressure, a severe headache, blurred vision, and pounding in your neck or ear.
  • Depression: mood changes, feelings of self-worth devaluation, a loss of interest in the things you liked, sleep issues, thoughts about harming yourself.
  • Swelling in your ankles, hands, or feet, or lumps in your breasts.
  • Shifts in the pattern or intensity of migraine headaches.

Common adverse effects of Kalliga could include:

  • Nausea, weight gain, vomiting, breast tenderness, bleeding that is not
  • Acne, darkening or sagging of facial skin.
  • Issues with contact lenses.

This is not an exhaustive list of probable side effects, and others may arise. Contact your physician to seek medical advice on the effects. You can report any adverse reactions to the FDA at 1-800-FDA-1088.


Do not use pills to control your birth if you are pregnant or just had a baby. It is best not to take birth control drugs if you are suffering from heart issues, bleeding from the vagina, liver issues, and severe migraine headaches in the event that you are also taking certain hepatitis C medications, when you're scheduled to undergo major surgery, if you smoke and you are over 35 years old, or if you have ever suffered an attack on your heart, a stroke, a blood clot, jaundice that is caused by birth control pills, or cancers of the uterus, breasts, or vagina.

Before you take this drug

Utilizing contraceptive pills may increase the risk of stroke, blood clots, and heart attacks. The risk is even higher if you suffer from hypertension, diabetes, high cholesterol, or are obese. Your risk of suffering from stroke or blood clots is greatest in the first year of being on birth control. The risk increases when you start taking birth control pills after not taking them for 4 weeks or more. Smoking could increase the chances of developing blood clots, heart attacks, or strokes that are caused by contraceptives, particularly when you are over 35. Do not take this if you're expecting. Stop using Kalliga and notify your doctor immediately if you find yourself pregnant or have missed two menstrual cycles in a row. If you've recently had an infant and are waiting at least 4 weeks before you start taking birth medication to control your pregnancy.

Do not use birth pills to control your birth if you are suffering from:

  • Untreated or uncontrolled blood pressure untreated or uncontrolled high blood pressure, cardiovascular disease (chest tension, coronary artery disease, a history of a heart attack or stroke, circulation issues, or a bleeding clot), or a higher chance of developing blood clots because of an issue with the heart or a hereditary blood disorder.
  • A history of cancer related to hormones as well as cancers of the breast, vagina, or uterus/cervix.
  • Abnormal vaginal bleeding that isn't being examined by the doctor.
  • Liver disease or liver cancer, if you take any hepatitis C medication containing ombitasvir, paritaprevir, or ritonavir with or without dasabuvir, or if you have a history of jaundice caused by pregnancy or birth control pills.
  • Serious migraine headaches (with an aura, numbness or weakening of vision, or other changes), particularly when you are older than 35 or you smoke and are over 35.

Speak to your doctor if you have ever suffered from:

  • Heart disease, high blood pressure, varicose veins, or if you're susceptible to blood clots, have high cholesterol, triglycerides, or are overweight.
  • Depression, migraine headaches, diabetes gallbladder problems.
  • kidney or liver disease.
  • Abnormal menstrual cycle, fibrocystic breast disease lumps, nodules, or abnormal mammograms.

Check with your doctor for advice on whether it is safe to breastfeed while taking this medication.

How to take birth control pills?

Follow the directions on the prescription label and go through all medication guides or instructions. Follow the medication exactly as prescribed. The initial pill is taken the day you begin your menstrual cycle or on the first Sunday following your period. It is possible to require additional birth control options, like condoms or fertilizer, before you take this medication. Follow the directions of your doctor.

Each day, take one pill for at least 24 hours. If the pills are empty, then start a fresh pack the next day. It is possible to become pregnant if you take a pill every day. Refill your prescription before you are completely out of pills. Certain birth control kits contain seven "reminder" pills to keep you on the same cycle. Your period is usually scheduled to begin when you're using these pills as reminders. There is a possibility of bleeding that has exploded. Contact your doctor if it persists or becomes very heavy. Utilize a backup birth control plan if you're sick and suffering from severe vomiting. Any surgeon or doctor who treats you needs to know that you are taking birth control medications. When you are taking birth control pills, you'll have to see your doctor often. Keep at room temperature, away from heat and moisture.

What happens if I miss a dose?

Follow the instructions on the prescription label and take note of all medication guides and instruction sheets. In the event of missing a dose, you increase the likelihood of becoming pregnant. If you do not take one active pill, you should take two pills during the day if you can remember. Then, take one pill a day for the remainder of the package. If you don't take two active tablets in one row during the first or second week, you should take two pills daily for two days. Then, take one pill a day throughout the remainder of the week. Make sure to use a backup birth control plan for up to 7 consecutive days after the missing pills.

If you fail to take two active pills consecutively during Week 3, you can throw out the rest of your pack and start a fresh pack the next day when you are a day 1 starter. If you're the Sunday starter, you should continue taking a pill each day through Sunday. On Sunday, toss out the rest of your pack and begin a new one the following day. If you do not take 3 active pills in one row during the week of 1–2, or 3, discard the remainder of your pack and begin a fresh pack the next day if you're a day 1 starter. If you're a Sunday-based starter, continue taking a dose throughout the day up to Sunday. When you are done, take out the rest of your pack and start a fresh one for the day. If you take 2 or 3 pills per day, it is possible that you will not have a period throughout the month. If you don't have your period for more than two consecutive months, consult your physician because there is a possibility that you are pregnant. If you don't remember a pill, discard it and take one pill a day until your pack is completely empty.

What happens if I overdose?

Get medical attention immediately or contact the Poison Help line at 1-800-222-1222. Overdose symptoms can include nausea, vomiting, and vaginal bleeding.

What should be avoided?

Don't smoke when using birth control medications, especially if you are over 35 years old. The use of birth control pills will make it impossible to stop your illness from spreading. Do not engage in unprotected sexual relations or share toothbrushes or razors. Discuss with your doctor ways to stop HIV transmission in sex.

Interaction with other drugs

Discuss with your doctor any other medications you take, including:

  • Phenylbutazone.
  • Griseofulvin.
  • Bosentan.
  • Rifampin.
  • St. John's wort.
  • Glecaprevir/pibrentasvir.
  • Anticonvulsants (antiepileptics) like carbamazepine, phenytoin, phenobarbital, and oxcarbazepine. Other examples include lamotrigine, topiramate, or felbamate.

This list isn't complete. Other medications could influence Kalliga, which includes prescription and over-the-counter medicines, vitamins, and herbal supplements. The interactions of all drugs are listed here.