Daklinza

What is Daklinza?

Daklinza can be described as an antiviral medication that stops the hepatitis C virus (HCV) from multiplying throughout your body. Daklinza is used in conjunction with other drugs for the treatment of chronic hepatitis C in adults. Daklinza is a treatment for specific types of hepatitis C in certain individuals. Make sure you only take the medicines that are prescribed to you. Don't share your medication with anyone else. Daklinza should be used together with other antiviral drugs and is not to be taken on its own. It is usually administered in combination with sofosbuvir, with or without ribavirin. Daklinza is used occasionally by those who also suffer from HIV. Daclatasvir cannot be used as a cure to treat HIV or AIDS.

Warnings

If you've had any experience with Hepatitis B, the virus could become active or worsen when you use or quit using Daklinza. It is possible that you will require regular liver function tests over many months. Inform your doctor about the medicines you are currently taking and all the ones you begin or stop taking. A variety of drugs interact, and certain drugs shouldn't be taken together. Daklinza is often used in conjunction with other medications. Check out the medication guide or patient's instructions that come with every medication that you take in a treatment combination. Do not change your dosage or schedule of medication without the advice of your physician.

Before you take this drug

Do not take Daklinza if you have an allergy to daclatasvir. When you take Daklinza together with other medications to ensure that the medicines you take are suitable for you, inform your physician about all of your medical conditions, including if you're nursing or pregnant. Many drugs can interact with each other and create dangerous consequences. Certain drugs shouldn't be used with daclatasvir. Your doctor could alter your treatment regimen if you are taking:

• Rifampin.
• John's Wort.
• Seizure medicine: carbamazepine and phenytoin.

To ensure that Daklinza is safe for you, inform your physician if you've ever experienced:

• Hepatitis B.
• Liver disorders other than liver problems other than C.
• An organ transplant.
• Diabetes.
• Heart disease.
• If you've recently taken an anti-heart rhythm medication called amodarone.
• If you are using an anticoagulant (warfarin, Coumadin, or Jantoven) and you're undergoing regular "INR" or prothrombin time tests.

Daklinza can be utilized in conjunction with ribavirin. Both women and men who are taking ribavirin must use effective birth control in order to stop the birth of a baby. Ribavirin can cause birth defects, miscarriage, or even the death of an unborn child if the father or mother is taking this medication. Ribavirin is not advisable to take when you are pregnant or if you're male and your sexual partner is expecting. Make use of effective birth control methods to avoid the possibility of pregnancy. Use birth control for at least six months following your last dose of ribavirin. Inform your doctor immediately. If you become pregnant during the time that both the mother and father are taking the drug ribavirin, It is not recommended to breastfeed while taking this medication. Consult your physician regarding any risks. Daklinza is not a product that has been approved to be used by anyone younger than 18 years of age.

How to take Daklinza?

Consume Daklinza exactly as directed by your physician. Follow the directions on the prescription label. Don't take this medication in greater or lesser quantities or for a longer time than prescribed. Your doctor will conduct blood tests to confirm that there are no issues that could make it unsafe for you to use Daklinza. Daklinza is a drink that can be taken either with or without food.

You'll require frequent blood tests to monitor your liver's functioning. If you've had any experience with Hepatitis B, the virus could become active or worse during the time you're using this medication or during the following months after stopping. It is possible that you will require a liver function test a few months after the last dose. Take all medications according to the directions, and follow the medication guide you are given. Do not alter your dose or dosing schedule without a doctor's approval. Everyone suffering from chronic hepatitis should stay under the supervision of a physician. It is not advisable to stop taking Daklinza suddenly. Stopping suddenly could make your hepatitis C more difficult to treat with antiviral medications. Keep at room temperature, free of heat and moisture.

Details on dosage

Usual Adult Dose for Chronic Hepatitis C:

60 mg taken orally every day
Recommended Regimen and Duration of Therapy:
Genotype 1: Without any cirrhosis: daclatasvir plus sofosbuvir for 12 weeks
Compensated (Child-Pugh A) liver disease: daclatasvir plus sofosbuvir for 12 weeks
compensated (Child-Pugh B and C) Cirrhosis: Daclatasvir plus sofosbuvir plus the drug ribavirin for 12 weeks
Daclatasvir plus sofosbuvir plus ribavirin for 12 weeks after transplant
Genotype 3: Without the cirrhosis, Daclatasvir was taken together with sofosbuvir for 12 weeks.
Compensated (Child-Pugh A) or decompensated (Child-Pugh B or C) Cirrhosis: daclatasvir and sofosbuvir in combination with ribavirin over 12 weeks
Daclatasvir plus sofosbuvir plus ribavirin for 12 weeks after transplant
Comments:  Dose guidelines also apply to patients suffering from HCV or HIV-1 who are coinfected with the virus.
The ideal duration of treatment is not known for patients suffering from HCV genotype 3 with cirrhosis or for HCV genotype 1-infected patients who suffer from cirrhosis caused by Child-Pugh.
The information provided by the manufacturer for sofosbuvir must be reviewed before dosing. The information from the manufacturer of the product is recommended for the dosage of ribavirin and dose adjustments (if necessary).
Use: In combination with sofosbuvir (with or without ribavirin) to treat chronic HCV genotypes 1 or 3.

What happens if I miss a dose?

Contact your doctor for advice when you have missed the dose. Make sure you refill your prescription before the expiration date of your medication.

What happens if I overdose?

For medical emergencies, seek emergency medical attention or contact the Poison Help line toll-free at 1-800-222-1222.

What should be avoided

This medicine won't hinder the spread of your illness. Be sure not to engage in unprotected sexual activity or share toothbrushes and razors. Consult your doctor regarding safe methods to avoid hepatitis C transmission during sexual contact. Sharing needles for medicine or drugs is never safe for healthy individuals.

Side effects of Daklinza

See a doctor immediately. Get medical attention immediately if you show symptoms of an allergy reaction. Daklinza: hives, breathing problems, or swelling of your lips, tongue, throat, or face.

See your doctor right away. If you are suffering from:

• Red blood cell count is low (anemia): pale skin, unusual fatigue, feeling lightheaded or short of breath, cold feet and hands.
• New or deteriorating symptoms in the liver: right-sided stomach discomfort, vomiting, decreased appetite, the appearance of your skin is yellowing or your eyes are yellowing, and you are not feeling well.

If you are taking Daklinza with sofosbuvir and you also use a heart-rhythm medicine known as amiodarone, This combination of medications can have dangerous side effects for your heart. Seek medical attention immediately. If you are taking any of these medicines and you suffer from:

• Extremely slow heartbeats; chest discomfort; shortness of breath.
• Confusion, memory issues, memory issues, confusion.
• Weakness, extreme fatigue weakness, extreme tiredness, and a lightheaded feeling (like you could faint).

Common Daklinza side effects may include:

• Nausea.
• Headache.
• Anemia.
• Feeling exhausted.

This is not a comprehensive list of all the possible side effects. Other side effects could occur. Contact your doctor for medical advice on the consequences. You can report adverse reactions to the FDA at 1-800-FDA-1088.

Interaction with other drugs

If you begin or stop using Daklinza, your doctor might have to adjust the dosages of other medications you are taking regularly. Numerous drugs may interact with daclatasvir, and certain drugs shouldn't be combined. This covers OTC and prescription drugs, vitamins, and herbal supplements. Not all interactions are included in this guideline. Discuss with your doctor any medications you take as well as any medications you begin or stop using in the course of treatment for this medication. Provide a complete list of your medications to any health professional who cares for you.