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Cetrotide (injectable)

Generic Name: Cetrorelix (injectables) [Se-troerel-ix]
Brand names: Cetrotide
Drug class: gonadotropin-releasing hormone antagonists

What is Cetrotide?

Cetrotide, a synthetic form of the protein, blocks the effects of certain hormones that are present in the body and controls ovulation. The eggs can be damaged if ovulation happens too early during fertility treatments. This medicine prevents eggs from being released prematurely (premature ovulation).Cetrotide prevents premature ovulation when controlled ovarian stimuli are used.Cetrotide can be used in other ways not mentioned in this guide.

Side effects of Cetrotide

If you experience any of the following symptoms: difficulty breathing; hives, rash, or swelling; a cough; or feeling light-headed, seek emergency medical attention.

Some women who use cetrotide may develop a condition known as ovarian hyperstimulation (OHSS), particularly after the first treatment. OHSS is a potentially life-threatening condition.

If any of these symptoms occur, immediately consult a medical provider.

  • Stomach pain, bloating;
  • Nausea, vomiting, diarrhoea;
  • Rapid weight gain in the face and midsection, especially
  • There is little or no urine production.
  • Feeling short of breath, especially when lying down, is a sign that you are having difficulty breathing.

Some of the common side effects associated with cetrotide include:

  • Nausea;
  • Headache
  • Redness, bruising, or itching may occur where the medicine has been injected.

There may be other side effects.Call your physician if experiencing side effects; for medical guidance call your provider; the FDA can be reached at 1-800-FDA-1088 if reporting side effects is necessary.

Warnings

Cetrotide should not be used if your kidneys are severely damaged, you are pregnant or breastfeeding, or you've ever had an allergy reaction to any medicine that is similar to Cetrotide (such as Lupron Antagon Zoladex Synarel or Zoladex).

Before you take this drug

Cetrotide should not be used if you have an allergy to it or:

  • You have severe kidney disease.
  • You are pregnant.
  • You are breastfeeding a child.
  • You are allergic to mannitol.
  • Have you experienced an allergic reaction from taking other gonadotropin-releasing hormone medications (like Lupron, Antagon, Zoladex Synarel etc)

Cetrotide can cause birth defects or miscarriages if used by women who are pregnant. Do not use it if pregnant. A negative pregnancy test may be required before you begin treatment.

It is unknown if cetrorelix can pass into breast milk or if this could harm a baby who is nursing. Cetrotide should not be used while breastfeeding.

Tell your doctor about any of the following to ensure that cetrotide will not harm you:

  • Kidney disease
  • Liver disease.

How to take Cetrotide?

Do not alter the instructions on your prescription. Use this medication only as directed. Do not exceed the prescribed dosage or extend usage beyond what is deemed safe.Cetrotide injections are given under the skin. You may be taught how to inject at home. You should not administer this medication to yourself if you don't know how to properly use the needles or syringes.Cetrotide comes as a powder that needs to be diluted with liquid before use. You should know how to mix and store your injections if you use them at home.Your healthcare provider will show you the best spots on your body where you can inject Cetrotide. Each time you inject cetrotide, use a new location. Don't inject in the same spot twice.

Read any patient information, medication guide, or instruction sheet. If you have questions, ask your doctor or pharmacist.Cetrotide should be started on a specific day in your cycle for best results. You should follow your doctor's instructions on when to take this medication and what time to inject it.You will receive a second medication called human chorionic gonadotrotropin (hcg) as part of your fertility treatments. You will only receive an hcg shot on the days that your ovaries are prepared for controlled ovulation.

You'll need to have regular ultrasound exams to determine if your ovaries are ready for ovulation. Your doctor can then determine the best time to administer your hcg.Cetrotide should be stored in the refrigerator. Do not freeze. To protect the medicine from light, keep it in its original container. Do not use any medicine after the date of expiration printed on the label.Only use a disposable syringe and needle once. Use syringes and needles only once. Seek advice from your pharmacist on the proper disposal method of sharps in puncture-proof containers that should remain out of the reach of pets and children.

What happens if I miss the dose?

If you forget to take a cetrotide dose, call your doctor. Do not miss any doses. Your fertility treatment will be successful if you use the right timing for your injections.

What happens if I overdose?

Reach out immediately if a poison-related emergency arises by dialling 1-800-222-1222 for poison assistance and seek immediate medical care. A cetrorelix overdose is unlikely to cause life-threatening symptoms.

What should be avoided?

If your doctor prescribes any restrictions regarding food, beverage, or activity, follow their instructions.

Interaction with other drug

Other drugs, such as vitamins and herbal remedies, may interact with cetrorelix. Inform your healthcare providers of all the medicines you are taking and those you plan to take.